LAUSR

Bioactivation mechanisms of N‐hydroxyaristolactams: Nitroreduction metabolites of aristolochic acids

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0 Published in 2019 at "Environmental and Molecular Mutagenesis"

DOI: 10.1002/em.22321

Abstract: Aristolochic acids (AAs) are human nephrotoxins and carcinogens found in concoctions of Aristolochia plants used in traditional medicinal practices worldwide. Genotoxicity of AAs is associated with the formation of active species catalyzed by metabolic enzymes,… read more here.

Keywords: strains expressing; aristolochic acids; expressing human; mechanisms hydroxyaristolactams ... See more keywords