Production of bioactive cyclotides: a comprehensive overview
Sign Up to like & getrecommendations! Published in 2020 at "Phytochemistry Reviews"
DOI: 10.1007/s11101-020-09682-9
Abstract: Cyclotides are an emerging class of disulfide-rich plant cyclic peptides, believed to be present in plants for defence purposes. Their exceptional thermal, chemical and enzymatic stabilities make them suitable as therapeutic agents, agrochemicals, molecular imaging… read more here.
Keywords: production; bioactive cyclotides; plant; cyclotides comprehensive ... See more keywords
Abstract A134: Therapeutic targeting of Hdm2/HdmX E3 ligase with bioactive cyclotides
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Cancer Therapeutics"
DOI: 10.1158/1535-7163.targ-19-a134
Abstract: Reactivation of tumor-suppressor p53 for targeted cancer therapy is an attractive strategy for cancers bearing wild-type (WT) p53. Targeting the Hdm2-p53 interface or HdmX-p53 interface or both has been a focus in the field. However,… read more here.
Keywords: hdmx; hdm2 hdmx; p53; bioactive cyclotides ... See more keywords