Computational analyses of interactions between ALK-5 and bioactive ligands: insights for the design of potential anticancer agents
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Biomolecular Structure and Dynamics"
DOI: 10.1080/07391102.2017.1404938
Abstract: Activin Receptor-Like Kinase 5 (ALK-5) is related to some types of cancer, such as breast, lung, and pancreas. In this study, we have used molecular docking, molecular dynamics simulations, and free energy calculations in order… read more here.
Keywords: analyses interactions; interactions alk; computational analyses; bioactive ligands ... See more keywords
Recent Progresses in Conjugation with Bioactive Ligands to Improve the Anticancer Activity of Platinum Compounds.
Sign Up to like & getrecommendations! Published in 2021 at "Current medicinal chemistry"
DOI: 10.2174/0929867328666210806110857
Abstract: Platinum (Pt) drugs, including cisplatin, are widely used for the treatment of solid tumors. Despite the clinical success, side effects and occurrence of resistance represent major limitations to the use of clinically available Pt drugs.… read more here.
Keywords: recent progresses; platinum; progresses conjugation; bioactive ligands ... See more keywords