The role of bioactive lipids in attenuating the neuroinflammatory cascade in traumatic brain injury
Sign Up to like & getrecommendations! Published in 2020 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.51240
Abstract: Traumatic brain injury (TBI) is a major cause of morbidity, mortality, and economic burden. Despite this, there are no proven medical therapies in the pharmacologic management of TBI. A better understanding of disease pathophysiology might… read more here.
Keywords: lipids attenuating; brain injury; traumatic brain; bioactive lipids ... See more keywords
Bioactive Lipids in Cancer, Inflammation and Related Diseases : Acute and Chronic Mild Traumatic Brain Injury Differentially Changes Levels of Bioactive Lipids in the CNS Associated with Headache.
Sign Up to like & getrecommendations! Published in 2019 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-21735-8_16
Abstract: Headache is a common complaint after mild traumatic brain injury (mTBI). Changes in the CNS lipidome were previously associated with acrolein-induced headache in rodents. mTBI caused similar headache-like symptoms in rats; therefore, we tested the… read more here.
Keywords: traumatic brain; bioactive lipids; mtbi; mild traumatic ... See more keywords
Bioactive Lipids in Age-Related Disorders.
Sign Up to like & getrecommendations! Published in 2020 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-42667-5_3
Abstract: Our own studies and those of others have shown that defects in essential fatty acid (EFA) metabolism occurs in age-related disorders such as obesity, type 2 diabetes mellitus, hypertension, atherosclerosis, coronary heart disease, immune dysfunction… read more here.
Keywords: age related; lipids age; bioactive lipids; acid ... See more keywords
ApoA-I mimetics favorably impact cyclooxygenase 2 and bioactive lipids that may contribute to cardiometabolic syndrome in chronic treated HIV.
Sign Up to like & getrecommendations! Published in 2021 at "Metabolism: clinical and experimental"
DOI: 10.1016/j.metabol.2021.154888
Abstract: OBJECTIVE We investigated whether apolipoprotein A-I (apoA-I) mimetic peptides 4F and 6F can be a novel therapeutic strategy to reduce blood and gut bioactive lipids, proinflammatory effects of endotoxin (LPS) and aberrant activation of cyclooxygenase… read more here.
Keywords: syndrome chronic; cardiometabolic syndrome; bioactive lipids; treated hiv ... See more keywords
The Spatiotemporal Dynamics of Low-abundance Bioactive Lipids in Arteries Undergoing Restenosis Observed and Identified at High Spatial Resolving Power with Multi-modal Mass Spectrometry Imaging
Sign Up to like & getrecommendations! Published in 2020 at "Microscopy and Microanalysis"
DOI: 10.1017/s1431927620021844
Abstract: The most common remedy for reduced or obstructed circulation is balloon angioplasty. While acutely effective, the treatment causes restenosis in a high fraction of patients via neointimal lesions. A significant barrier to unravelling the mechanisms… read more here.
Keywords: restenosis; spatiotemporal dynamics; mass spectrometry; bioactive lipids ... See more keywords
Lipidomics of Cell Secretome Combined with the Study of Selected Bioactive Lipids in an In Vitro Model of Osteoarthritis
Sign Up to like & getrecommendations! Published in 2022 at "Stem Cells Translational Medicine"
DOI: 10.1093/stcltm/szac045
Abstract: Abstract Analytical advancements in lipidomics have enabled large-scale investigations of lipid biology. Herein, we focused on four bioactive lipid families, namely polyunsaturated fatty acids, eicosanoids, endocannabinoids, and N-acylethanolamines, and their involvement in the mesenchymal stem… read more here.
Keywords: model osteoarthritis; tnf; vitro model; pea ... See more keywords
Bioactive lipids in osteoarthritis: risk or benefit?
Sign Up to like & getrecommendations! Published in 2018 at "Current Opinion in Rheumatology"
DOI: 10.1097/bor.0000000000000463
Abstract: Purpose of review Lipids are bioactive molecules that can affect several biological functions. Technological developments allowing identification of novel lipid species and the study of their function have led to a significant advance in our… read more here.
Keywords: risk; lipids osteoarthritis; osteoarthritis; osteoarthritis risk ... See more keywords
Bioactive lipids and pathological retinal angiogenesis
Sign Up to like & getrecommendations! Published in 2019 at "British Journal of Pharmacology"
DOI: 10.1111/bph.14507
Abstract: Angiogenesis, disruption of the retinal barrier, leukocyte‐adhesion and oedema are cardinal signs of proliferative retinopathies that are associated with vision loss. Therefore, identifying factors that regulate these vascular dysfunctions is critical to target pathological angiogenesis.… read more here.
Keywords: proliferative retinopathies; lipids pathological; angiogenesis; pathological retinal ... See more keywords
Bioactive lipids and their metabolism: New therapeutic opportunities for Parkinson's disease
Sign Up to like & getrecommendations! Published in 2021 at "European Journal of Neuroscience"
DOI: 10.1111/ejn.15566
Abstract: Parkinson's disease (PD) is a neurological disorder characterized by motor dysfunction, which can also be associated with non‐motor symptoms. Its pathogenesis is thought to stem from a loss of dopaminergic neurons in the substantia nigra… read more here.
Keywords: lipids metabolism; parkinson disease; new therapeutic; bioactive lipids ... See more keywords
Bioactive lipids and metabolic syndrome—a symposium report
Sign Up to like & getrecommendations! Published in 2022 at "Annals of the New York Academy of Sciences"
DOI: 10.1111/nyas.14752
Abstract: Recent research has shed light on the cellular and molecular functions of bioactive lipids that go far beyond what was known about their role as dietary lipids. Bioactive lipids regulate inflammation and its resolution as… read more here.
Keywords: symposium report; metabolic syndrome; syndrome symposium; lipids metabolic ... See more keywords
Association of Physical Activity With Bioactive Lipids and Cardiovascular Events
Sign Up to like & getrecommendations! Published in 2022 at "Circulation Research"
DOI: 10.1161/circresaha.122.320952
Abstract: Background: To clarify the mechanisms underlying physical activity (PA)-related cardioprotection, we examined the association of PA with plasma bioactive lipids (BALs) and cardiovascular disease (CVD) events. We additionally performed genome-wide associations. Methods: PA-bioactive lipid associations… read more here.
Keywords: physical activity; activity bioactive; case control; bioactive lipids ... See more keywords