Rational Design of a Highly Specific Prolyl Endopeptidase To Activate the Antihypertensive Effect of Peptides
Sign Up to like & getrecommendations! Published in 2023 at "ChemBioChem"
DOI: 10.1002/cbic.202200691
Abstract: Enzymatic hydrolysis of food‐derived proteins to produce bioactive peptides could activate food functions such as antihypertension. However, the diversity of enzymatic hydrolysis products can reduce bioactive peptides’ efficacy. Highly specific proteases can homogenize the hydrolysis… read more here.
Keywords: prolyl endopeptidase; bioactive peptides; highly specific; antihypertensive effect ... See more keywords
Current trends and perspectives on bioaccessibility and bioavailability of food bioactive peptides: in vitro and ex vivo studies.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.12077
Abstract: Bioaccesibility and bioavailability of food derived bioactive compounds are important issues for the assessment of their in vivo physiological health promoting effects. Food components such as proteins and peptides are exposed to different proteases and… read more here.
Keywords: bioavailability food; bioaccesibility; food; bioactive peptides ... See more keywords
Omics-prediction of bioactive peptides from the edible cyanobacterium Arthrospira platensis proteome.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.8546
Abstract: BACKGROUND Bioinformatics approaches are widely used to evaluate the prospects of novel protein sources in bioactive peptide research. Edible cyanobacteria are considered as potential protein precursors. However, the abundance of unicellular cyanobacterial proteins is largely… read more here.
Keywords: bioactive peptides; arthrospira platensis; platensis proteome;
Bioinformatics and peptidomics approaches to the discovery and analysis of food-derived bioactive peptides
Sign Up to like & getrecommendations! Published in 2018 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-018-0974-1
Abstract: There are emerging advancements in the strategies used for the discovery and development of food-derived bioactive peptides because of their multiple food and health applications. Bioinformatics and peptidomics are two computational and analytical techniques that… read more here.
Keywords: food derived; bioinformatics peptidomics; bioactive peptides; food ... See more keywords
Potential anticarcinogenic effect of goat milk-derived bioactive peptides on HCT-116 human colorectal carcinoma cell line.
Sign Up to like & getrecommendations! Published in 2021 at "Analytical biochemistry"
DOI: 10.1016/j.ab.2021.114166
Abstract: Novel food-derived anti cancerogenic bioactive peptides were characterized by goat milk pepsin hydrolysate. Pepsin treated casein fraction of goat milk caused an apoptotic cell death on the HCT116 cell lines. These bioactive peptides are encrypted… read more here.
Keywords: cell; effect goat; goat milk; bioactive peptides ... See more keywords
An Updated review on production of food derived bioactive peptides; focus on the psychrotrophic bacterial proteases
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DOI: 10.1016/j.bcab.2021.102051
Abstract: Abstract Psychrotrophs or psychrophiles are extremophilic microorganisms that have the maximum temperature above 20 °C for growth. Since around 70% of the earth’s biosphere temperature is below 5 °C, psychrotrophs could be found in diversity… read more here.
Keywords: updated review; food; bioactive peptides; review production ... See more keywords
Generation of bioactive peptides from duck meat during post-mortem aging.
Sign Up to like & getrecommendations! Published in 2017 at "Food chemistry"
DOI: 10.1016/j.foodchem.2017.05.094
Abstract: The objective of this study was to investigate the endogenous release of bioactive peptides in duck meat during 7days of post-mortem aging. The degradation of muscle proteins led to release of small peptides ( read more here.
Keywords: duck meat; bioactive peptides; post mortem;
Generation of bioactive peptides during food processing.
Sign Up to like & getrecommendations! Published in 2018 at "Food chemistry"
DOI: 10.1016/j.foodchem.2017.06.119
Abstract: Large amounts of peptides are naturally generated in foods through the proteolysis phenomena taking place during processing. Such proteolysis is carried out either by endogenous enzymes in ripened foods or by the combined action of… read more here.
Keywords: processing; peptides food; generation bioactive; bioactive peptides ... See more keywords
Identification of new bioactive peptides from Kefir milk through proteopeptidomics: Bioprospection of antihypertensive molecules.
Sign Up to like & getrecommendations! Published in 2019 at "Food chemistry"
DOI: 10.1016/j.foodchem.2019.01.010
Abstract: Kefir, a probiotic beverage prepared from fermented milk, has been associated with antihypertensive activity. However, the bioactive molecules responsible for this activity still remain unclear. Therefore, in this study we aim to evaluate the mechanisms… read more here.
Keywords: milk; peptides kefir; identification new; new bioactive ... See more keywords
Simulated gastrointestinal digestion of camel and bovine casein hydrolysates: Identification and characterization of novel anti-diabetic bioactive peptides.
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DOI: 10.1016/j.foodchem.2021.129374
Abstract: Camel milk proteins are an important substrate for bioactive peptides generation. This study investigates in-vitro antidiabetic effect (via inhibition of α-amylase (AA), α-glucosidase (AG) and dipeptidyl peptidase IV (DPP-IV)) of bovine (BC) and camel casein… read more here.
Keywords: camel; gastrointestinal digestion; bovine; simulated gastrointestinal ... See more keywords
Characterisation of the in vitro bioactive properties of alkaline and enzyme extracted brewers' spent grain protein hydrolysates.
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DOI: 10.1016/j.foodres.2018.12.008
Abstract: Brewer's spent grain (BSG) is a co-product of the brewing industry that has been shown to contain a range of bioactive peptides encrypted within its protein sequences. Two methods were evaluated herein to generate bioactive… read more here.
Keywords: spent grain; bsg; bioactive peptides; bsg hydrolysates ... See more keywords