Synthesis and Bioactivity Evaluation of Novel N-Pyridylpyrazolemethanamine Derivatives
Sign Up to like & getrecommendations! Published in 2018 at "Chemical Research in Chinese Universities"
DOI: 10.1007/s40242-018-8083-4
Abstract: To further explore the structure-activity relationship(SAR) of amide bridge moeity of anthranilic diamides derivatives, a series of N-pyridylpyrazole derivatives was designed, synthesized and their biological activities were evaluated. The chemical structures of novel target compounds… read more here.
Keywords: evaluation novel; novel pyridylpyrazolemethanamine; bioactivity evaluation; pyridylpyrazolemethanamine derivatives ... See more keywords
Design, Synthesis, And Preliminary Bioactivity Evaluation Of 2,7-Substituted Carbazole Derivatives As Potent Autotaxin Inhibitors And Antitumor Agents.
Sign Up to like & getrecommendations! Published in 2018 at "Anti-cancer agents in medicinal chemistry"
DOI: 10.2174/1871520618666180830161821
Abstract: BACKGROUND Autotaxin-LPA signaling has been implicated in cancer progression, and targeted for the discovery of cancer therapeutic agents. OBJECTIVE Potential ATX inhibitors were synthesized to develop novel leading compounds and effective anticancer agents. METHOD The… read more here.
Keywords: design synthesis; bioactivity evaluation; preliminary bioactivity; synthesis preliminary ... See more keywords