Sign Up to like & get
recommendations!
0
Published in 2019 at "Journal of pharmaceutical and biomedical analysis"
DOI: 10.1016/j.jpba.2019.113019
Abstract: Corynantheidine, a minor alkaloid found in Mitragyna speciosa (Korth.) Havil, has been shown to bind to opioid receptors and act as a functional opioid antagonist, but its unique contribution to the overall properties of kratom…
read more here.
Keywords:
corynantheidine;
method development;
pharmacokinetic studies;
analysis ... See more keywords
Sign Up to like & get
recommendations!
0
Published in 2020 at "Journal of pharmaceutical and biomedical analysis"
DOI: 10.1016/j.jpba.2020.113466
Abstract: The purpose of this work was to develop and validate a rapid, sensitive and robust liquid chromatography tandem mass spectrometric method for the quantification of β-lapachone in human plasma and to use that method to…
read more here.
Keywords:
liquid;
lapachone;
human plasma;
method ... See more keywords
Sign Up to like & get
recommendations!
0
Published in 2021 at "Journal of chromatographic science"
DOI: 10.1093/chromsci/bmab094
Abstract: A chemometrics-oriented green ultra-performance liquid chromatography-mass spectrometry/mass spectrometry method was developed and validated for the first-time simultaneous estimation of capecitabine (CAP) and lapatinib (LPB) along with imatinib (as internal standard (IS)) in rat plasma. Analytes…
read more here.
Keywords:
rat plasma;
validation;
simultaneous estimation;
method ... See more keywords
Sign Up to like & get
recommendations!
1
Published in 2022 at "Molecules"
DOI: 10.3390/molecules27020457
Abstract: Background: The stability of a drug or metabolites in biological matrices is an essential part of bioanalytical method validation, but the justification of its sample size (replicates number) is insufficient. The international guidelines differ in…
read more here.
Keywords:
method validation;
confidence intervals;
bioanalytical method;
stability ... See more keywords
Sign Up to like & get
recommendations!
1
Published in 2022 at "Molecules"
DOI: 10.3390/molecules27207117
Abstract: Xanthohumol (XH) a prenylated chalcone has diverse therapeutic effects against various diseases. In the present study, a bioanalytical method was developed for XH in rat plasma using reverse phase high performance liquid chromatography. The validation…
read more here.
Keywords:
validation;
bioanalytical method;
rat plasma;
plasma ... See more keywords
Sign Up to like & get
recommendations!
0
Published in 2020 at "Bioanalysis"
DOI: 10.4155/bio-2020-0065
Abstract: Once released, the ICH M10 Guideline on bioanalytical method validation will become one of the most important milestones in the history of regulated bioanalysis, closing a chapter on intense discussions among the industry and health…
read more here.
Keywords:
bioanalysis;
bioanalytical method;
guideline bioanalytical;
method validation ... See more keywords
Sign Up to like & get
recommendations!
0
Published in 2017 at "Journal of AOAC International"
DOI: 10.5740/jaoacint.16-0204
Abstract: The present work relates to the development and validation of reversed-phase HPLC-UV-photodiode array methods for the estimation of two drugs in blood serum: dronedarone hydrochloride (DDN), a class III antiarrhythmic drug, and duloxetine hydrochloride (DLX),…
read more here.
Keywords:
validation;
dronedarone;
blood serum;
bioanalytical method ... See more keywords