REGEN-COV® antibody cocktail bioanalytical strategy: comparison of LC-MRM-MS and immunoassay methods for drug quantification
Sign Up to like & getrecommendations! Published in 2021 at "Bioanalysis"
DOI: 10.4155/bio-2021-0190
Abstract: Aim: In response to the COVID-19 pandemic, Regeneron developed the anti-SARS-CoV-2 monoclonal antibody cocktail, REGEN-COV® (RONAPREVE® outside the USA). Drug concentration data was important for determination of dose, so a two-part bioanalytical strategy was implemented… read more here.
Keywords: drug; regen cov; bioanalytical strategy; antibody cocktail ... See more keywords
Bioanalytical strategy for the characterization and bioanalysis of biologics: a global, nonregulated bioanalytical lab perspective.
Sign Up to like & getrecommendations! Published in 2023 at "Bioanalysis"
DOI: 10.4155/bio-2022-0215
Abstract: Over the past two decades, we have seen an increase in the complexity and diversity of biotherapeutic modalities pursued by biopharmaceutical companies. These biologics are multifaceted and susceptible to post-translational modifications and in vivo biotransformation… read more here.
Keywords: bioanalysis biologics; global nonregulated; characterization bioanalysis; bioanalytical strategy ... See more keywords