Articles with "bioassay guided" as a keyword



Bioassay‐Guided Extraction and Isolation of Natural Herbicides from Dried Zanthoxylum limonella Alston Fruits

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Published in 2024 at "Asian Journal of Organic Chemistry"

DOI: 10.1002/ajoc.202400317

Abstract: Weeds are problematic plant species around the world. Various strategies exist for controlling weeds, but chemical treatment remains the preferred method, particularly when using natural substances. In this research, a crude aqueous‐methanol extract from dried… read more here.

Keywords: seed; zanthoxylum limonella; dried zanthoxylum; bioassay guided ... See more keywords

Bioassay-guided fractionations of Cannabis sativa extract and HPLC-assisted purifications of anti-proliferative active fractions lead to the isolation of 16 known and one new phytomolecule and their in-silico analysis

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Published in 2024 at "Medicinal Chemistry Research"

DOI: 10.1007/s00044-024-03199-y

Abstract: The comprehensive anti-cancer activities of cannabinoid acids and non-cannabinoids are not fully explored. Herein we report simple extraction, faster bioassay-guided fractionation, and HPLC-assisted purification of bioactive secondary metabolite and their identification. Anti-proliferative activity of six… read more here.

Keywords: non cannabinoids; hplc assisted; cannabis sativa; bioassay guided ... See more keywords

Bioassay-guided isolation of antioxidant and α-glucosidase inhibitory constituents from stem of Vigna angularis.

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Published in 2019 at "Bioorganic chemistry"

DOI: 10.1016/j.bioorg.2019.03.041

Abstract: Stem of Vigna angularis (Willd.) Ohwi & H. Ohashi (VAS) is a main byproduct with considerable bioactivities. In present study, a bioassay-guided phytochemical investigation was used and led to the isolation of 16 compounds including… read more here.

Keywords: bioassay guided; vigna angularis; stem vigna; glucosidase ... See more keywords

Bioassay-guided isolation of antifungal amides against Sclerotinia sclerotiorum from the seeds of Clausena lansium

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Published in 2018 at "Industrial Crops and Products"

DOI: 10.1016/j.indcrop.2018.05.037

Abstract: Abstract Clausena lansium (Lour.) Skeels is an attractive shrub or small tree, a member of the Rutaceae family. The seeds, leaves and roots of this plant have been used as herbal medicines for a long… read more here.

Keywords: sclerotinia sclerotiorum; bioassay guided; clausena lansium; sclerotiorum ... See more keywords

Bioassay-guided fractionation and identification of wound healing active compound from Pistacia vera L. hull extract.

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Published in 2019 at "Journal of ethnopharmacology"

DOI: 10.1016/j.jep.2019.112335

Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Pistachio hull has traditionally been used to treat peptic ulcer, hemorrhoids, oral and cutaneous wounds. AIM OF THE STUDY On the basis of its traditional uses and previous pharmacological reports, a bioassay guided… read more here.

Keywords: wound healing; active compound; guided fractionation; vera ... See more keywords

Bioassay-guided isolation and evaluation of anti-osteoporosis active polysaccharides from Morinda officinalis.

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Published in 2020 at "Journal of ethnopharmacology"

DOI: 10.1016/j.jep.2020.113113

Abstract: ETHNOPHARMACOLOGICAL RELEVANCE As a famous Chinese tonic herb for the bones and joints, the clinical efficacy of Morinda officinalis has shown its advantages in the treatment of bone disease. However, the anti-osteoporosis potential and responsible… read more here.

Keywords: anti osteoporosis; bioassay guided; morinda officinalis; guided isolation ... See more keywords

Bioassay-guided isolation of antiplasmodial and antimicrobial constituents from the roots of Terminalia albida.

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Published in 2020 at "Journal of ethnopharmacology"

DOI: 10.1016/j.jep.2020.113624

Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Terminalia albida (Combretaceae), widely used in Guinean traditional medicine, showed promising activity against Plasmodium falciparum and Candida albicans in previous studies. Bioassay-guided fractionation was carried out in order to isolate the compounds responsible… read more here.

Keywords: bioassay guided; guided isolation; terminalia albida; isolation antiplasmodial ... See more keywords

Acetylcholinesterase‐inhibitory activity of Iranian plants: Combined HPLC/bioassay‐guided fractionation, molecular networking and docking strategies for the dereplication of active compounds

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Published in 2018 at "Journal of Pharmaceutical and Biomedical Analysis"

DOI: 10.1016/j.jpba.2018.06.026

Abstract: HIGHLIGHTSPrangos ferulacea was the most active plant against the acetylcholinesterase enzyme.Metabolites were analyzed by bioassay‐guided fractionation and molecular networking.Phytochemical analysis of the active extract led to the identification of 17 compounds.Flavonoids showed a high affinity… read more here.

Keywords: guided fractionation; bioassay guided; fractionation molecular; molecular networking ... See more keywords

Bioassay-guided isolation of urease inhibitors from Ferula narthex Bioss

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Published in 2019 at "South African Journal of Botany"

DOI: 10.1016/j.sajb.2018.07.011

Abstract: Abstract The current study was designed to evaluate the urease inhibitory activities of the fractions of Ferula narthex Bioss, followed by bioassay guided isolation of new urease sesquiterpene coumarins, as potential urease inhibitors. The chloroform… read more here.

Keywords: urease inhibitors; ferula narthex; bioassay guided; narthex bioss ... See more keywords
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Bioassay-Guided Isolation of Antibacterial Metabolites from Emericella sp. TJ29.

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Published in 2017 at "Journal of natural products"

DOI: 10.1021/acs.jnatprod.7b00077

Abstract: Bioassay-guided isolation of metabolites from cultures of the plant-derived fungus Emericella sp. TJ29 yielded three new terpene-polyketide hybrid meroterpenoids, emervaridones A-C (1-3), two new polyketides, varioxiranediols A and B (5 and 6), and three known… read more here.

Keywords: bioassay guided; isolation antibacterial; guided isolation; emericella tj29 ... See more keywords

Bioassay-Guided Isolation and Identification of Cytotoxic Compounds from Melaleuca quinquenervia Fruits

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Published in 2024 at "ACS Omega"

DOI: 10.1021/acsomega.4c00769

Abstract: The fruit extract of Melaleuca quinquenervia yielded a total of 19 compounds, including two novel spiro-biflavonoid enantiomers (1a and 1b) and a chalcone derivative (3). Their structures were determined through spectroscopic analysis. The enantiomers of… read more here.

Keywords: isolation identification; melaleuca quinquenervia; guided isolation; quinquenervia ... See more keywords