N-trimethyl chitosan coated targeting nanoparticles improve the oral bioavailability and antioxidant activity of vitexin.
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DOI: 10.1016/j.carbpol.2022.119273
Abstract: Vitexin is a flavonoid which exerted many protective activities. However, the low bioavailability discounts the in vivo effects of vitexin. This study designed vitexin loaded bilayer nanoparticles by the assembly of soybean peptides and the… read more here.
Keywords: vitexin; trimethyl chitosan; bioavailability antioxidant; antioxidant activity ... See more keywords
Synthesis, biological and computational studies of flavonoid acetamide derivatives
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DOI: 10.1039/d2ra01375d
Abstract: This study reports the synthesis and characterization of a novel class of flavonoid acetamide derivatives (FA) of quercetin, apigenin, fisetin, kaempferol, and luteolin. Flavonoids display numerous biological properties but are limited by aqueous insolubility, enzymatic… read more here.
Keywords: flavonoid acetamide; bioavailability; admet toxicity; acetamide derivatives ... See more keywords
Bioavailability and antioxidant activity of nanotechnology-based botanic antioxidants.
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DOI: 10.1111/1750-3841.15582
Abstract: Botanic bioactive substances have issues with their solubility, stability, and oral bioavailability in the application, which could be improved by nanotechnologies. In another hands, green synthesis of nanoparticles (NPs) with plant extract is also a… read more here.
Keywords: antioxidant activity; bioavailability; activity nanotechnology; bioavailability antioxidant ... See more keywords