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Published in 2022 at "British Journal of Clinical Pharmacology"
DOI: 10.1111/bcp.15545
Abstract: Anaphylaxis guidelines recommend intramuscular adrenaline, commonly 300 μg administered using an auto‐injector device. However, overweight/obese patients may require a higher adrenaline dose for adequate cardiovascular (CV) response. This study evaluated the pharmacokinetics (PK) and pharmacodynamic (PD)…
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Keywords:
bioavailability cardiovascular;
injector healthy;
auto injector;
cardiovascular effects ... See more keywords