Articles with "bioavailability cardiovascular" as a keyword



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Bioavailability and cardiovascular effects of adrenaline administered by Anapen 500 μg auto‐injector in healthy volunteers

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Published in 2022 at "British Journal of Clinical Pharmacology"

DOI: 10.1111/bcp.15545

Abstract: Anaphylaxis guidelines recommend intramuscular adrenaline, commonly 300 μg administered using an auto‐injector device. However, overweight/obese patients may require a higher adrenaline dose for adequate cardiovascular (CV) response. This study evaluated the pharmacokinetics (PK) and pharmacodynamic (PD)… read more here.

Keywords: bioavailability cardiovascular; injector healthy; auto injector; cardiovascular effects ... See more keywords