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Enhanced Oral Bioavailability of Diltiazem by the Influence of Gallic Acid and Ellagic Acid in Male Wistar Rats: Involvement of CYP3A and P‐gp Inhibition

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Published in 2017 at "Phytotherapy Research"

DOI: 10.1002/ptr.5873

Abstract: The oral bioavailability of diltiazem is very low due to rapid first pass metabolism in liver and intestine. The purpose of the study was to investigate the effect of gallic acid and ellagic acid on… read more here.

Keywords: ellagic acid; oral bioavailability; bioavailability diltiazem; diltiazem ... See more keywords