Co-encapsulation of Egg-White-Derived Peptides (EWDP) and Curcumin within the Polysaccharide-Based Amphiphilic Nanoparticles for Promising Oral Bioavailability Enhancement: Role of EWDP.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.1c08186
Abstract: The comprehensive utilization of food-derived nutraceuticals with different polarities has been extremely restricted by their poor bioavailability and coexistence in a single system. This study aimed to fabricate a self-assembly of amphiphilic nanoparticles (NPs) for… read more here.
Keywords: oral bioavailability; ewdp; promising oral; amphiphilic nanoparticles ... See more keywords
A Compendium of Bioavailability Enhancement via Noisome Technology.
Sign Up to like & getrecommendations! Published in 2023 at "Pharmaceutical nanotechnology"
DOI: 10.2174/2211738511666230309104323
Abstract: BACKGROUND Bioavailability is the dissimilarity between the total amount of drug exposure to a person and the actual dose received by his body. The difference in bioavailability between formulations of a given drug can have… read more here.
Keywords: technology; niosomal technology; bioavailability; drug ... See more keywords
Fenofibrate Nanocrystals Embedded in Oral Strip-Films for Bioavailability Enhancement
Sign Up to like & getrecommendations! Published in 2018 at "Bioengineering"
DOI: 10.3390/bioengineering5010016
Abstract: The aim of the present study was to make a fenofibrate (FNB) nanocrystal (NC) by wet media milling, characterizations and formulates into oral strip-films (OSFs). Mechanical properties, redispersion study, and solid-state characterizations results suggested that… read more here.
Keywords: bioavailability enhancement; strip films; drug; oral strip ... See more keywords
Bioavailability Enhancement Techniques for Poorly Aqueous Soluble Drugs and Therapeutics
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10092055
Abstract: The low water solubility of pharmacoactive molecules limits their pharmacological potential, but the solubility parameter cannot compromise, and so different approaches are employed to enhance their bioavailability. Pharmaceutically active molecules with low solubility convey a… read more here.
Keywords: solubility; bioavailability; soluble drugs; drug ... See more keywords
Strategies for Solubility and Bioavailability Enhancement and Toxicity Reduction of Norcantharidin
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27227740
Abstract: Cantharidin (CTD) is the main active ingredient isolated from Mylabris, and norcantharidin (NCTD) is a demethylated derivative of CTD, which has similar antitumor activity to CTD and lower toxicity than CTD. However, the clinical use… read more here.
Keywords: strategies solubility; bioavailability; toxicity; solubility bioavailability ... See more keywords