Comparison of the physicochemical properties, aqueous solubility, and oral bioavailability of rivaroxaban-loaded high-pressure homogenised and Shirasu porous glass membrane emulsified solid self-nanoemulsifying drug delivery systems
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Molecular Liquids"
DOI: 10.1016/j.molliq.2021.117057
Abstract: Abstract This study aimed to compare high-pressure homogenization (HPH) and Shirasu porous glass (SPG) membrane emulsification for enhancing the oral bioavailability of rivaroxaban using a self-nanoemulsifying drug delivery system (SNEDDS). The effects of two different… read more here.
Keywords: high pressure; drug; bioavailability rivaroxaban; calcium silicate ... See more keywords
Chitosan caged liposomes for improving oral bioavailability of rivaroxaban: in vitro and in vivo evaluation
Sign Up to like & getrecommendations! Published in 2020 at "Pharmaceutical Development and Technology"
DOI: 10.1080/10837450.2020.1870237
Abstract: Abstract In this study, chitosan (CS) caged classic liposomes (CLs) and flexible liposomes (FLs) were developed to enhance the oral bioavailability of rivaroxaban (RVX) in the fasted condition. The prepared formulations were subjected to physicochemical… read more here.
Keywords: liposomes improving; oral bioavailability; rvx; bioavailability rivaroxaban ... See more keywords