Discovery of Potent, Orally Bioavailable Sphingosine-1-Phosphate Transporter (Spns2) Inhibitors
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DOI: 10.1021/acs.jmedchem.4c00879
Abstract: Targeting the S1P pathway has resulted in the development of S1P1 receptor modulators for the treatment of multiple sclerosis and ulcerative colitis. We hypothesize that targeting an upstream node of the S1P pathway may provide… read more here.
Keywords: bioavailable sphingosine; spns2; orally bioavailable; discovery potent ... See more keywords