Mental health in the UK Biobank: A roadmap to self-report measures and neuroimaging correlates.
Sign Up to like & getrecommendations! Published in 2021 at "Human brain mapping"
DOI: 10.1002/hbm.25690
Abstract: The UK Biobank (UKB) is a highly promising dataset for brain biomarker research into population mental health due to its unprecedented sample size and extensive phenotypic, imaging, and biological measurements. In this study, we aimed… read more here.
Keywords: biobank; report measures; self report; health ... See more keywords
An Introduction to Starting a Biobank.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8935-5_2
Abstract: The purpose of a biobank is to process, organize, and maintain various types of biospecimens that are to be utilized for both clinical and research-based services. There are different types of biobanks, so the goals… read more here.
Keywords: introduction starting; biobank; starting biobank; biology ... See more keywords
Quality assessment on the long-term cryopreservation and nucleic acids extraction processes implemented in the andalusian public biobank
Sign Up to like & getrecommendations! Published in 2019 at "Cell and Tissue Banking"
DOI: 10.1007/s10561-019-09764-9
Abstract: Human samples are commonly collected and long-term stored in biobanks for current and future analyses. Even though techniques for freezing human blood are well established, the storage time can compromise the cell viability as well… read more here.
Keywords: quality; nucleic acids; long term; biobank ... See more keywords
Returning actionable genomic results in a research biobank: Analytic validity, clinical implementation, and resource utilization.
Sign Up to like & getrecommendations! Published in 2021 at "American journal of human genetics"
DOI: 10.1016/j.ajhg.2021.10.005
Abstract: Over 100 million research participants around the world have had research array-based genotyping (GT) or genome sequencing (GS), but only a small fraction of these have been offered return of actionable genomic findings (gRoR). Between… read more here.
Keywords: actionable genomic; research; biobank; returning actionable ... See more keywords
China Kadoorie Biobanks: Opportunities for Personalized Medicine And Pharmacogenomics
Sign Up to like & getrecommendations! Published in 2019 at "European Neuropsychopharmacology"
DOI: 10.1016/j.euroneuro.2017.06.072
Abstract: Abstract Chronic diseases, such as stroke, heart disease, cancer and mental disorder, are the leading causes of disability and death worldwide. Despite recent advances, our ability to prevent and treat these conditions is still limited.… read more here.
Keywords: medicine; kadoorie biobanks; biobank; biobanks opportunities ... See more keywords
20 ANALYSIS OF A BROAD DEPRESSION PHENOTYPE IN UK BIOBANK
Sign Up to like & getrecommendations! Published in 2019 at "European Neuropsychopharmacology"
DOI: 10.1016/j.euroneuro.2017.08.021
Abstract: Background Major Depressive Disorder (MDD) is substantially heritable but has been late to reveal its genetic associations. New data available from UK Biobank (UKB) presents a new opportunity to test for common genetic associations with… read more here.
Keywords: phenotype; depression; biobank; analysis broad ... See more keywords
United Kingdom Biobank (UK Biobank): JACC Focus Seminar 6/8.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the American College of Cardiology"
DOI: 10.1016/j.jacc.2021.03.342
Abstract: An increasing number of people are now living with cardiovascular disease (CVD), with concomitant CVD-related hospitalizations, operations, and prescriptions. To ultimately deliver optimal cardiovascular care, access to population-based biobanks with data on multiomics, phenotypes, and… read more here.
Keywords: united kingdom; biobank; biobank jacc; kingdom biobank ... See more keywords
Establishment of a biobank for human lung tissues of congenital diaphragmatic hernia and congenital pulmonary airway malformation.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of pediatric surgery"
DOI: 10.1016/j.jpedsurg.2019.05.003
Abstract: BACKGROUND Human tissue samples are an invaluable and little available source of information for translational studies of congenital lung diseases such as Congenital Diaphragmatic Hernia (CDH) or Congenital Pulmonary Airway Malformation (CPAM). PURPOSE We aimed… read more here.
Keywords: biobank; diaphragmatic hernia; lung; cdh ... See more keywords
UK Biobank shares the promise of big data
Sign Up to like & getrecommendations! Published in 2018 at "Nature"
DOI: 10.1038/d41586-018-06948-3
Abstract: UK Biobank contains a wealth of data on genetics, health and more from 500,000 participants. A detailed overview of the biobank and an analysis of its brain-imaging data show the value of this resource.A bank… read more here.
Keywords: big data; promise big; biobank; shares promise ... See more keywords
Imputation of behavioral candidate gene repeat variants in 486,551 publicly-available UK Biobank individuals
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Human Genetics"
DOI: 10.1038/s41431-019-0349-x
Abstract: Some of the most widely studied variants in psychiatric genetics include variable number tandem repeat variants (VNTRs) in SLC6A3, DRD4, SLC6A4, and MAOA. While initial findings suggested large effects, their importance with respect to psychiatric… read more here.
Keywords: variants 486; biobank individuals; available biobank; biobank ... See more keywords
Biomarker genetics
Sign Up to like & getrecommendations! Published in 2021 at "Nature Reviews Nephrology"
DOI: 10.1038/s41581-021-00400-y
Abstract: Biomarkers are often used to diagnose and monitor chronic diseases, and greater understanding of how genetic variants associate with biomarker levels has potential to aid risk stratification and identify new therapeutic targets. an analysis of… read more here.
Keywords: risk; biomarker; biobank; genetics ... See more keywords