Evidence of epistasis in regions of long-range linkage disequilibrium across five complex diseases in the UK Biobank and eMERGE datasets
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DOI: 10.1101/2022.10.19.22280888
Abstract: Leveraging linkage disequilibrium (LD) patterns as representative of population substructure enables the discovery of additive association signals in genome-wide association studies (GWAS). Standard GWAS are well-powered to interrogate additive models; however, new approaches are required… read more here.
Keywords: linkage disequilibrium; across five; long range; range ... See more keywords