Biochemical and clinical biomarkers in adult SMA 3–4 patients treated with nusinersen for 22 months
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DOI: 10.1002/acn3.51625
Abstract: To investigate biomarkers of disease progression in cerebrospinal fluid (CSF) and serum in adult patients with spinal muscular atrophy (SMA). Furthermore, we assess the clinical response to nusinersen treatment in adults with SMA over a… read more here.
Keywords: adult sma; biochemical clinical; clinical biomarkers; patients treated ... See more keywords
Biochemical and Clinical Aspects of Hereditary Tyrosinemia Type 1.
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DOI: 10.1007/978-3-319-55780-9_2
Abstract: Inborn errors of metabolism (IEMs) are a group of diseases involving a genetic defect that alters a metabolic pathway and that presents usually during infancy. The tyrosine degradation pathway contains five enzymes, four of which… read more here.
Keywords: biochemical clinical; hereditary tyrosinemia; tyrosinemia type; disease ... See more keywords
Biochemical and clinical relevance of alpha lipoic acid: antioxidant and anti-inflammatory activity, molecular pathways and therapeutic potential
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DOI: 10.1007/s00011-017-1079-6
Abstract: BackgroundThe molecular nature of lipoic acid (LA) clarifies its capability of taking part to a variety of biochemical reactions where redox state is meaningful. The pivotal action of LA is the antioxidant activity due to… read more here.
Keywords: biochemical clinical; several diseases; activity; lipoic acid ... See more keywords
Refining the Definitions of Biochemical and Clinical Cure for Primary Aldosteronism Using the Primary Aldosteronism Surgical Outcome (PASO) Classification System
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DOI: 10.1007/s00268-017-4311-1
Abstract: IntroductionDetermination of outcomes after adrenalectomy for primary aldosteronism (PA) is limited by the lack of standardized definitions of cure. The Primary Aldosteronism Surgical Outcomes (PASO) group recently established new consensus definitions for biochemical and clinical… read more here.
Keywords: aldosteronism; primary aldosteronism; paso; biochemical clinical ... See more keywords
Biochemical, clinical, demographic and imaging biomarkers for disease progression in knee osteoarthritis.
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DOI: 10.2217/bmm-2021-0579
Abstract: Aim: To identify prognostic biomarker(s) for knee osteoarthritis (OA) in the Osteoarthritis Initiative (OAI) cohort. Methods: Multilevel regression was used to determine the association between baseline biomarkers and change in biomarkers from baseline to 24… read more here.
Keywords: knee osteoarthritis; progression; disease progression; biochemical clinical ... See more keywords
Implementation of a biochemical, clinical, and genetic screening programme for familial hypercholesterolemia in 26 centres in Spain: The ARIAN study
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.971651
Abstract: Background: Familial hypercholesterolemia (FH) is clearly underdiagnosed and undertreated. The aim of this present study is to assess the benefits of FH screening through a joint national program implemented between clinical laboratories and lipid units.… read more here.
Keywords: familial hypercholesterolemia; biochemical clinical; hypercholesterolemia; score ... See more keywords
Biochemical and clinical evaluation of endothelial injury after distal or traditional transradial access in percutaneous interventions.
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DOI: 10.33963/kp.a2022.0108
Abstract: BACKGROUND Distal transradial access (dTRA) has been proposed as an alternative to traditional transradial access (TRA) in cardiac catheterization. AIMS The aim of the study was to compare these two transradial approaches: TRA and dTRA… read more here.
Keywords: endothelial injury; biochemical clinical; traditional transradial; access ... See more keywords
Prevalence, Biochemical and Clinical Characteristics of Resistant Hypertension
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DOI: 10.37358/rc.18.10.6637
Abstract: The objectives of the present study were to evaluate the prevalence of resistant hypertension (RH) in primary care setting and to analyse its biochemical and clinical characteristics. After 3 months of treatment and evaluation, 721… read more here.
Keywords: resistant hypertension; hypertension; hypertension prevalence; clinical characteristics ... See more keywords