Exploring the Biochemical Foundations of a Successful GLUT1-Targeting Strategy to BNCT: Chemical Synthesis and In Vitro Evaluation of the Entire Positional Isomer Library of ortho-Carboranylmethyl-Bearing Glucoconjugates.
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DOI: 10.1021/acs.molpharmaceut.0c00917
Abstract: Boron neutron capture therapy (BNCT) is a noninvasive binary therapeutic modality applicable to the treatment of cancers. While BNCT offers a tumor-targeting selectivity that is difficult to match by other means, the last obstacles preventing… read more here.
Keywords: biochemical foundations; foundations successful; ortho carboranylmethyl; glut1 ... See more keywords