Biochemical profiling of anti-HIV prodrug Elsulfavirine (Elpida®) and its active form VM1500A against a panel of twelve human carbonic anhydrase isoforms
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Enzyme Inhibition and Medicinal Chemistry"
DOI: 10.1080/14756366.2021.1927007
Abstract: Abstract The non-nucleoside reverse transcriptase inhibitor VM1500A is approved for the treatment of HIV/AIDS in its N-acyl sulphonamide prodrug form elsulfavirine (Elpida®). Biochemical profiling against twelve human carbonic anhydrase (CA, EC 4.2.1.1) isoforms showed that… read more here.
Keywords: carbonic anhydrase; human carbonic; biochemical profiling; anhydrase isoforms ... See more keywords
Biochemical Profiling of Smokeless Tobacco Product Kiwam at Different Processing Steps
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DOI: 10.1200/jgo.18.79602
Abstract: Introduction: Kiwam (qiwam) is a partially fermented tobacco product consumed with betel quid (paan). The major constituents of this product are tobacco, saffron (zaffrani) and some other additives. It contains tobacco-specific nitrosamines (TSNA) which is… read more here.
Keywords: tobacco; tobacco product; steps biochemical; biochemical profiling ... See more keywords
Biochemical profiling of metabolomics in heavy metal-intoxicated impaired metabolism and its amelioration using plant-based bioactive compound
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DOI: 10.3389/fmolb.2022.1029729
Abstract: Exposure to Pb is widely spreading and has far-reaching negative effects on living systems. This study aimed to investigate the toxic effects of Pb, through biochemical profiling and the ameliorative effects of quercetin against Pb-toxicity.… read more here.
Keywords: metabolism; group received; group; crn group ... See more keywords
Biodiversity, Biochemical Profiling, and Pharmaco-Commercial Applications of Withania somnifera: A Review
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DOI: 10.3390/molecules28031208
Abstract: Withania somnifera L. Dunal (Ashwagandha), a key medicinal plant native to India, is used globally to manage various ailments. This review focuses on the traditional uses, botany, phytochemistry, and pharmacological advances of its plant-derived constituents.… read more here.
Keywords: profiling pharmaco; review; withania somnifera; biodiversity biochemical ... See more keywords