Association of HSD3B1 Genotype With Response to Androgen-Deprivation Therapy for Biochemical Recurrence After Radiotherapy for Localized Prostate Cancer
Sign Up to like & getrecommendations! Published in 2018 at "JAMA Oncology"
DOI: 10.1001/jamaoncol.2017.3164
Abstract: Importance The variant HSD3B1 (1245C) allele enhances dihydrotestosterone synthesis and predicts resistance to androgen-deprivation therapy (ADT) for biochemically recurrent prostate cancer after prostatectomy and for metastatic disease. Whether this is true after radiotherapy is unknown.… read more here.
Keywords: radiotherapy; biochemical recurrence; prostate cancer; variant alleles ... See more keywords
Different predictive values of microvessel density for biochemical recurrence among different PCa populations: A systematic review and meta‐analysis
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DOI: 10.1002/cam4.5093
Abstract: Several studies have explored the relationship between intratumoral microvessel density (MVD) and the risk of postoperative biochemical recurrence (BCR) in prostate cancer (PCa), although the results are contradictory. Therefore, we conducted a meta‐analysis to investigate… read more here.
Keywords: biochemical recurrence; microvessel density; meta analysis; pca ... See more keywords
Prospective comparison of whole-body MRI and 68Ga-PSMA PET/CT for the detection of biochemical recurrence of prostate cancer after radical prostatectomy
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s00259-019-04308-5
Abstract: PurposeTo assess whole-body magnetic resonance imaging (wb-MRI) for detection of biochemical recurrence in comparison to 68Ga-prostate-specific membrane antigen positron emission tomography/computed tomography (68Ga-PSMA PET/CT) in prostate cancer (Pca) patients after radical prostatectomy.MethodsThis was a prospective… read more here.
Keywords: psma pet; biochemical recurrence; detection; 68ga psma ... See more keywords
Primary tumour PSMA intensity is an independent prognostic biomarker for biochemical recurrence-free survival following radical prostatectomy
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s00259-022-05756-2
Abstract: The prognostic value of PSMA intensity on PSMA PET/CT due to underlying biology and subsequent clinical implications is an emerging topic of interest. We sought to investigate whether primary tumour PSMA PET intensity contributes to… read more here.
Keywords: radical prostatectomy; intensity; biochemical recurrence; psma intensity ... See more keywords
Evaluation of tumor morphologies and association with biochemical recurrence after radical prostatectomy in grade group 5 prostate cancer
Sign Up to like & getrecommendations! Published in 2017 at "Virchows Archiv"
DOI: 10.1007/s00428-017-2241-9
Abstract: We assessed Gleason pattern 5 (GP5) and other prostatic adenocarcinoma (PCa) morphologies to determine their association with biochemical recurrence (BCR). A search for grade group 5 PCa with radical prostatectomy (RP) yielded 49 patients. RPs… read more here.
Keywords: association biochemical; group; grade group; radical prostatectomy ... See more keywords
The significance of micro-lymphatic invasion and pathological Gleason score in prostate cancer patients with pathologically organ-confined disease and negative surgical margins after robot-assisted radical prostatectomy
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Clinical Oncology"
DOI: 10.1007/s10147-019-01561-4
Abstract: Background The development process of recurrence in prostate cancer patients with pathologically organ-confined (pT2) disease and negative surgical margins is unclear. The aim of the present study was to determine factors associated with the development… read more here.
Keywords: surgical margins; recurrence; prostate cancer; cancer patients ... See more keywords
Small-volume lymph node involvement and biochemical recurrence after robot-assisted radical prostatectomy with extended lymph node dissection in prostate cancer
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Clinical Oncology"
DOI: 10.1007/s10147-020-01682-1
Abstract: Background We investigated prognostic factors for biochemical recurrence (BCR) after robot-assisted radical prostatectomy (RARP) with extended pelvic lymph node (LN) dissection. Methods We included 173 patients who underwent RARP with extended pelvic LN dissection without… read more here.
Keywords: bcr; risk; positive lns; dissection ... See more keywords
The Perineural Invasion Paradox: Is Perineural Invasion an Independent Prognostic Indicator of Biochemical Recurrence Risk in Patients With pT2N0R0 Prostate Cancer? A Multi-Institutional Study
Sign Up to like & getrecommendations! Published in 2019 at "Advances in Radiation Oncology"
DOI: 10.1016/j.adro.2018.09.006
Abstract: Purpose Perineural invasion (PNI) is a histologic feature that is present in as many as 84% of patients with prostate cancer. The prognostic significance of PNI is controversial, with recent studies yielding contradictory results. This… read more here.
Keywords: recurrence; perineural invasion; pni; gleason score ... See more keywords
Risk factors for biochemical recurrence after a tissue-ablative prostate-specific antigen
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DOI: 10.1016/j.brachy.2018.05.011
Abstract: PURPOSE A prostate-specific antigen (PSA) nadir read more here.
Keywords: prostate; risk; recurrence; psa nadir ... See more keywords
GBX2 Methylation Is a Novel Prognostic Biomarker and Improves Prediction of Biochemical Recurrence Among Patients with Prostate Cancer Negative for Intraductal Carcinoma and Cribriform Architecture.
Sign Up to like & getrecommendations! Published in 2019 at "European urology oncology"
DOI: 10.1016/j.euo.2018.08.003
Abstract: BACKGROUND Tumor intraductal carcinoma/cribriform architecture (IDC/C) is associated with an unfavorable prognosis and biochemical recurrence (BCR) in prostate cancer (PCa). Up to 70% of PCa patients are IDC/C-negative, but it is estimated that 20% of… read more here.
Keywords: bcr; cancer; methylation; biochemical recurrence ... See more keywords
External Validation of the European Association of Urology Biochemical Recurrence Risk Groups to Predict Metastasis and Mortality After Radical Prostatectomy in a European Cohort.
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DOI: 10.1016/j.eururo.2019.03.016
Abstract: The impact of biochemical recurrence (BCR) after radical treatment of prostate cancer on oncological outcomes remains unclear. A new European Association of Urology BCR risk stratification (low and high risk) has been proposed. To validate… read more here.
Keywords: risk; association urology; urology; radical prostatectomy ... See more keywords