NK cells are biologic and biochemical targets of 6-mercaptopurine in Crohn's disease patients.
Sign Up to like & getrecommendations! Published in 2017 at "Clinical immunology"
DOI: 10.1016/j.clim.2016.12.004
Abstract: NK cells, which contribute to immune defense against certain viral infections and neoplasia, are emerging as modifiers of chronic immunologic diseases including transplant rejection and autoimmune diseases. Immunobiology and genetic studies have implicated NK cells… read more here.
Keywords: biologic biochemical; cells biologic; targets mercaptopurine; disease ... See more keywords
Biochemical targets of drugs mitigating oxidative stress via redox-independent mechanisms.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical Society transactions"
DOI: 10.1042/bst20160473
Abstract: Acute or chronic oxidative stress plays an important role in many pathologies. Two opposite approaches are typically used to prevent the damage induced by reactive oxygen and nitrogen species (RONS), namely treatment either with antioxidants… read more here.
Keywords: drugs mitigating; redox; targets drugs; stress ... See more keywords