Biocompatible single-chain polymer nanoparticles loaded with an antigen mimetic as potential anticancer vaccine
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DOI: 10.1021/acsmacrolett.8b00052
Abstract: The “pancarcinoma” Tn antigen (αGalNAc-O-Ser/Thr) is a tumor-associated carbohydrate antigen (TACA) overexpressed on the surface of cancer cells and suitable target for anticancer vaccines. However, TACAs commonly show weak immunogenicity, low in vivo stability, and… read more here.
Keywords: antigen mimetic; chain polymer; biocompatible single; anticancer ... See more keywords