Tailored Bioorthogonal and Bioconjugate Chemistry: A Source of Inspiration for Developing Kinetic Target-Guided Synthesis Strategies.
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DOI: 10.1021/acs.bioconjchem.0c00568
Abstract: Kinetic target-guided synthesis (KTGS) is a promising tool for the discovery of biologically active compounds. It relies on the identification of potent ligands that are covalently assembled by the biological targets themselves from a pool… read more here.
Keywords: guided synthesis; target guided; chemistry; kinetic target ... See more keywords