Design, synthesis, and biodistribution studies of new analogues of marine alkaloids: Potent in vitro and in vivo fungicidal agents against Candida spp.
Sign Up to like & getrecommendations! Published in 2020 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2020.113048
Abstract: Invasive candidiasis, such as intra-abdominal candidiasis (IAC), is a significant cause of morbidity and mortality worldwide. IAC is still poorly understood, and its treatment represents a challenge for public health. In this study, we showed… read more here.
Keywords: design synthesis; vitro vivo; candida spp; biodistribution studies ... See more keywords
Adefovir dipivoxil loaded proliposomal powders with improved hepatoprotective activity: formulation, optimization, pharmacokinetic, and biodistribution studies
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Liposome Research"
DOI: 10.1080/08982104.2017.1363228
Abstract: Abstract The present study aimed to prepare proliposomal formulae for improving the oral bioavailability of adefovir dipivoxil (AD), a nucleoside reverse transcriptase inhibitor effective against hepatitis B virus (HBV). The prepared proliposomal formulae were characterized… read more here.
Keywords: biodistribution studies; adefovir dipivoxil; pharmacokinetic biodistribution; dipivoxil loaded ... See more keywords