Flexible multivariate nonlinear models for bioequivalence problems
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DOI: 10.1177/1471082x17706018
Abstract: Modelling the concentration of a drug in the bloodstream over time is usually done using compartment models. In pharmacokinetic data, they turn into highly nonlinear mixed-effects models (NLMEMs) when we take the heterogeneity between subjects… read more here.
Keywords: bioequivalence; models bioequivalence; nonlinear models; bioequivalence problems ... See more keywords