Cholesterol Microdomain Enhances the Biofilm Eradication of Antibiotic Liposomes
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202101745
Abstract: Resistance and tolerance of biofilms to antibiotics is the greatest challenge in the treatment of bacterial infections. Therefore, developing an effective strategy against biofilms is a top priority. Liposomes are widely used as antibiotic drug… read more here.
Keywords: microdomain enhances; biofilm eradication; cholesterol microdomain; antibiotic liposomes ... See more keywords
Identification of N‐Arylated NH125 Analogues as Rapid Eradicating Agents against MRSA Persister Cells and Potent Biofilm Killers of Gram‐Positive Pathogens
Sign Up to like & getrecommendations! Published in 2017 at "ChemBioChem"
DOI: 10.1002/cbic.201600622
Abstract: Bacterial biofilms housing dormant persister cells are innately tolerant to antibiotics and disinfectants, yet several membrane‐active agents are known to eradicate tolerant bacterial cells. NH125, a membrane‐active persister killer and starting point for development, led… read more here.
Keywords: agents mrsa; membrane active; persister cells; persister ... See more keywords
A New Method for Determination of Minimum Biofilm Eradication Concentration for Accurate Antimicrobial Therapy.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9118-1_6
Abstract: Antimicrobial susceptibility testing (AST) is an important technique to find the susceptibility pattern of clinical isolates in order to administer the appropriate drug. One such technique is minimum inhibitory concentration (MIC), which not only identifies… read more here.
Keywords: new method; eradication concentration; biofilm eradication; concentration ... See more keywords
Investigation on the biofilm eradication potential of selected medicinal plants against methicillin-resistant Staphylococcus aureus
Sign Up to like & getrecommendations! Published in 2020 at "Biotechnology Reports"
DOI: 10.1016/j.btre.2020.e00523
Abstract: Highlights • Investigation of A. indica, M. oleifera, M. koenigii and P. guajava extracts against MRSA biofilm.• Pet. ether extract of A. indica show superior antibiofilm activity.• Extracts are non-toxic with minimal hemolytic properties. read more here.
Keywords: eradication potential; investigation; potential selected; investigation biofilm ... See more keywords
Use of carvacrol, thymol, and eugenol for biofilm eradication and resistance modifying susceptibility of Salmonella enterica serovar Typhimurium strains to nalidixic acid.
Sign Up to like & getrecommendations! Published in 2017 at "Microbial pathogenesis"
DOI: 10.1016/j.micpath.2017.01.012
Abstract: The Aims of the study was to evaluate the antibacterial susceptibility and the biofilm eradication of three natural compounds carvacrol (CAR), thymol (TH) and eugenol (EUG), alone or in combination with nalidixic acid (NA) against… read more here.
Keywords: thymol eugenol; combination; susceptibility; biofilm ... See more keywords
New Perspectives in Biofilm Eradication.
Sign Up to like & getrecommendations! Published in 2018 at "ACS infectious diseases"
DOI: 10.1021/acsinfecdis.7b00170
Abstract: Microbial biofilms, which are elaborate and highly resistant microbial aggregates formed on surfaces or medical devices, cause two-thirds of infections and constitute a serious threat to public health. Immunocompromised patients, individuals who require implanted devices,… read more here.
Keywords: perspectives biofilm; new perspectives; biofilm; biofilm eradication ... See more keywords
Albumin-coated pH-responsive dimeric prodrug-based nano-assemblies with high biofilm eradication capacity.
Sign Up to like & getrecommendations! Published in 2022 at "Biomaterials science"
DOI: 10.1039/d2bm01520j
Abstract: Pseudomonas aeruginosa (PA) biofilms cause many persistent chronic infections in humans, especially in cystic fibrosis (CF) patients. The biofilms form a strong barrier which may inhibit antimicrobial agents from penetrating the biofilms and killing PA… read more here.
Keywords: dimeric prodrug; azm; tob; tob azm ... See more keywords
Effective Biofilm Eradication on Orthopedic Implants with Methylene Blue Based Antimicrobial Photodynamic Therapy In Vitro
Sign Up to like & getrecommendations! Published in 2023 at "Antibiotics"
DOI: 10.3390/antibiotics12010118
Abstract: Periprosthetic joint infections (PJI) are difficult to treat due to biofilm formation on implant surfaces, often requiring removal or exchange of prostheses along with long-lasting antibiotic treatment. This in vitro study investigated the effect of… read more here.
Keywords: vitro; methylene blue; photodynamic therapy; biofilm eradication ... See more keywords