Microbial biofilm correlates with an increased antibiotic tolerance and poor therapeutic outcome in infective endocarditis
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DOI: 10.1186/s12866-019-1596-2
Abstract: BackgroundInfective endocarditis (IE) is associated with high rates of mortality. Prolonged treatments with high-dose intravenous antibiotics often fail to eradicate the infection, frequently leading to high-risk surgical intervention. By providing a mechanism of antibiotic tolerance,… read more here.
Keywords: microbial biofilm; tolerance; biofilm growing; biofilm ... See more keywords