Acidity-Activatable Nanoparticles with Glucose Oxidase-Enhanced Photoacoustic Imaging and Photothermal Effect, and Macrophage-Related Immunomodulation for Synergistic Treatment of Biofilm Infection.
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DOI: 10.1002/smll.202204377
Abstract: The pH-responsive theragnostics exhibit great potential for precision diagnosis and treatment of diseases. Herein, acidity-activatable nanoparticles of GB@P based on glucose oxidase (GO) and polyaniline are developed for treatment of biofilm infection. Catalyzed by GO,… read more here.
Keywords: biofilm; treatment biofilm; biofilm infection; effect ... See more keywords
A Prospective, Randomized, Controlled Study to Evaluate the Effectiveness of a Fabric-based Wireless Electroceutical Dressing Compared to Standard of Care Treatment Against Acute Trauma and Burn Wound Biofilm Infection.
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DOI: 10.1089/wound.2023.0007
Abstract: OBJECTIVE Despite advances in the use of topical and parenteral antimicrobial therapy and the practice of early tangential burn-wound excision to manage bacterial load, 60% of the mortality from burns is attributed to bacterial biofilm… read more here.
Keywords: biofilm; biofilm infection; burn wound; infection ... See more keywords
Biofilms cause chronic infections.
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DOI: 10.12968/jowc.2017.26.8.423
Abstract: More important to wound care providers is this group, including individuals from across Europe and the US, used chronic wounds as one of their two examples of a biofilm infection, as evidence that biofilms are… read more here.
Keywords: wound; biofilm; wound care; biofilm infection ... See more keywords
Immunopathogenesis of Craniotomy Infection and Niche-Specific Immune Responses to Biofilm
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DOI: 10.3389/fimmu.2021.625467
Abstract: Bacterial infections in the central nervous system (CNS) can be life threatening and often impair neurological function. Biofilm infection is a complication following craniotomy, a neurosurgical procedure that involves the removal and replacement of a… read more here.
Keywords: craniotomy infection; immune responses; infection; biofilm ... See more keywords
Eradication of Staphylococcus aureus Biofilm Infection by Persister Drug Combination
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DOI: 10.3390/antibiotics11101278
Abstract: Staphylococcus aureus can cause a variety of infections, including persistent biofilm infections, which are difficult to eradicate with current antibiotic treatments. Here, we demonstrate that combining drugs that have robust anti-persister activity, such as clinafloxacin… read more here.
Keywords: combination; biofilm infection; aureus biofilm; biofilm ... See more keywords
Near‐infrared light-triggered nitric oxide nanocomposites for photodynamic/photothermal complementary therapy against periodontal biofilm in an animal model
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DOI: 10.7150/thno.83745
Abstract: Background: Periodontal disease, an oral disease that initiates with plaque biofilm infection, affects 10% of the global population. Due to the complexity of tooth root anatomy, biofilm resistance and antibiotic resistance, traditional mechanical debridement and… read more here.
Keywords: gas; nitric oxide; therapy; biofilm infection ... See more keywords