Combination and nanotechnology based pharmaceutical strategies for combating respiratory bacterial biofilm infections.
Sign Up to like & getrecommendations! Published in 2022 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2022.121507
Abstract: Respiratory infections are one of the major global health problems. Among them, chronic respiratory infections caused by biofilm formation are difficult to treat because of both drug tolerance and poor drug penetration into the complex… read more here.
Keywords: combating respiratory; respiratory biofilm; nanotechnology; pharmaceutical strategies ... See more keywords
Multiplexed Identification of Bacterial Biofilm Infections Based on Machine-Learning-Aided Lanthanide Encoding.
Sign Up to like & getrecommendations! Published in 2022 at "ACS nano"
DOI: 10.1021/acsnano.1c11333
Abstract: Pathogenic biofilms are up to 1000-fold more drug-resistant than planktonic pathogens and cause about 80% of all chronic infections worldwide. The lack of prompt and reliable biofilm identification methods seriously prohibits the diagnosis and treatment… read more here.
Keywords: cocktail kits; machine learning; learning aided; identification ... See more keywords
A DNase-mimetic artificial enzyme for the eradication of drug-resistant bacterial biofilm infections.
Sign Up to like & getrecommendations! Published in 2022 at "Nanoscale"
DOI: 10.1039/d1nr07629a
Abstract: The construction of multifunctional nano-enzymes is a feasible strategy for fighting multi-drug resistant (MDR) bacterial biofilm-associated infections. Extracellular DNA (eDNA) is an important functional part of biofilm formation, including the initial adherence of bacteria to… read more here.
Keywords: bacterial biofilm; biofilm; biofilm infections; drug resistant ... See more keywords
Amylase degradation enhanced NIR photothermal therapy and fluorescence imaging of bacterial biofilm infections.
Sign Up to like & getrecommendations! Published in 2022 at "Biomaterials science"
DOI: 10.1039/d2bm01570f
Abstract: Effective treatment of bacterial biofilm-related infections is a great challenge for the medical community. During the formation of biofilms, bacteria excrete extracellular polymeric substances (EPS), including polysaccharides, proteins, nucleic acids, etc., to encapsulate themselves and… read more here.
Keywords: photothermal therapy; fluorescence imaging; biofilm; biofilm infections ... See more keywords
The origin of extracellular DNA in bacterial biofilm infections in vivo
Sign Up to like & getrecommendations! Published in 2020 at "Pathogens and Disease"
DOI: 10.1093/femspd/ftaa018
Abstract: ABSTRACT Extracellular DNA (eDNA) plays an important role in both the aggregation of bacteria and in the interaction of the resulting biofilms with polymorphonuclear leukocytes (PMNs) during an inflammatory response. Here, transmission electron and confocal… read more here.
Keywords: extracellular dna; derived edna; dna; biofilm infections ... See more keywords
Antibiotic Resistance and Biofilm Infections in the NICUs and Methods to Combat It
Sign Up to like & getrecommendations! Published in 2023 at "Antibiotics"
DOI: 10.3390/antibiotics12020352
Abstract: Neonatal sepsis is an important cause of neonatal morbidity and mortality. A significant proportion of bacteria causing neonatal sepsis is resistant to multiple antibiotics, not only to the usual empirical first-line regimens, but also to… read more here.
Keywords: antibiotic resistance; nicus methods; infections nicus; biofilm infections ... See more keywords
The Usefulness of Microalgae Compounds for Preventing Biofilm Infections
Sign Up to like & getrecommendations! Published in 2019 at "Antibiotics"
DOI: 10.3390/antibiotics9010009
Abstract: Biofilms play an important role in infectious diseases. It has been estimated that most medical infections are due to bacterial biofilms, and about 60–70% of nosocomial infections are also caused by the formation of a… read more here.
Keywords: microalgae compounds; preventing biofilm; usefulness microalgae; biofilm infections ... See more keywords
Therapeutic Strategies against Biofilm Infections
Sign Up to like & getrecommendations! Published in 2023 at "Life"
DOI: 10.3390/life13010172
Abstract: A biofilm is an aggregation of surface-associated microbial cells that is confined in an extracellular polymeric substance (EPS) matrix. Infections caused by microbes that form biofilms are linked to a variety of animals, including insects… read more here.
Keywords: resistance; therapeutic strategies; strategies biofilm; biofilm infections ... See more keywords