RNA exosome mutations in pontocerebellar hypoplasia alter ribosome biogenesis and p53 levels
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DOI: 10.26508/lsa.202000678
Abstract: The work highlights the link between dysfunction of the RNA exosome, ribosome biogenesis, p53-dependent signalling, and apoptosis. Pontocerebellar hypoplasia caused by mutations of the exosome subunits could be classified as a ribosomopathy. The RNA exosome… read more here.
Keywords: rna exosome; biogenesis p53; p53; pontocerebellar hypoplasia ... See more keywords