Deciphering psoriasis. A bioinformatic approach.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of dermatological science"
DOI: 10.1016/j.jdermsci.2017.11.010
Abstract: BACKGROUND Psoriasis is an immune-mediated, inflammatory and hyperproliferative disease of the skin and joints. The cause of psoriasis is still unknown. The fundamental feature of the disease is the hyperproliferation of keratinocytes and the recruitment… read more here.
Keywords: disease; psoriasis bioinformatic; psoriasis; deciphering psoriasis ... See more keywords
The morbid cutaneous anatomy of the human genome revealed by a bioinformatic approach.
Sign Up to like & getrecommendations! Published in 2020 at "Genomics"
DOI: 10.1016/j.ygeno.2020.07.009
Abstract: Computational approaches have been developed to prioritize candidate genes in disease gene identification. They are based on different pieces of evidences associating each gene with the given disease. In this study, 648 genes underlying genodermatosis… read more here.
Keywords: morbid cutaneous; anatomy human; cutaneous anatomy; anatomy ... See more keywords
Molecular signature characters complement taxonomic diagnoses: a bioinformatic approach exemplified by ciliated protists (Ciliophora, Oligotrichea).
Sign Up to like & getrecommendations! Published in 2022 at "Molecular phylogenetics and evolution"
DOI: 10.1016/j.ympev.2022.107433
Abstract: Traditionally, taxa following the botanical or zoological codes of nomenclature are diagnosed mainly by morphological characters, although integrative taxonomy advocates including additional features. While many taxonomic studies include DNA sequence analyses, a systematic integration of… read more here.
Keywords: molecular signature; signature; characters complement; signature characters ... See more keywords
Unique bioinformatic approach and comprehensive reanalysis improve diagnostic yield of clinical exomes
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Human Genetics"
DOI: 10.1038/s41431-019-0401-x
Abstract: Clinical exome sequencing (CES) is increasingly being utilized; however, a large proportion of patients remain undiagnosed, creating a need for a systematic approach to increase the diagnostic yield. We have reanalyzed CES data for a… read more here.
Keywords: diagnostic yield; reanalysis; approach; bioinformatic approach ... See more keywords
A Bioinformatic Approach for the Identification of Molecular Determinants of Resistance/Sensitivity to Cancer Thermotherapy
Sign Up to like & getrecommendations! Published in 2019 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2019/4606219
Abstract: Application of heat above 43°C and up to 47°C, the so-called “thermal ablation” range, leads to tumor cell destruction either by apoptosis or by necrosis. However, tumor cells have developed mechanisms of defense that render… read more here.
Keywords: cancer; molecular determinants; bioinformatic approach; identification molecular ... See more keywords
A Bioinformatic Approach Based on Systems Biology to Determine the Effects of SARS-CoV-2 Infection in Patients with Hypertrophic Cardiomyopathy
Sign Up to like & getrecommendations! Published in 2022 at "Computational and Mathematical Methods in Medicine"
DOI: 10.1155/2022/5337380
Abstract: Recently, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), has infected millions of individuals worldwide. While COVID-19 generally affects the lungs, it also damages other organs, including those… read more here.
Keywords: hypertrophic cardiomyopathy; approach based; bioinformatic approach; based systems ... See more keywords
Novel Arginine- and Proline-Rich Candidacidal Peptides Obtained through a Bioinformatic Approach
Sign Up to like & getrecommendations! Published in 2023 at "Antibiotics"
DOI: 10.3390/antibiotics12030472
Abstract: Antimicrobial resistance is a major public health concern worldwide. Albeit to a lesser extent than bacteria, fungi are also becoming increasingly resistant to antifungal drugs. Moreover, due to the small number of antifungal classes, therapy… read more here.
Keywords: proline rich; bioinformatic approach; proline; arginine proline ... See more keywords