Articles with "bioinformatics analysis" as a keyword



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Screening and bioinformatics analysis of a ceRNA network based on the circular RNAs, miRNAs, and mRNAs in pan‐cancer

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Published in 2020 at "Cancer Medicine"

DOI: 10.1002/cam4.3375

Abstract: The pan‐cancer analysis has recently brought us into a novel level of cancer research. Nowadays, the Circular RNAs (circRNAs) is becoming increasingly important in the occurrence and progression of tumors. Nevertheless, the specific expression patterns… read more here.

Keywords: pan cancer; circular rnas; bioinformatics analysis; screening bioinformatics ... See more keywords
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Identification of MEG8/miR‐378d/SOBP axis as a novel regulatory network and associated with immune infiltrates in ovarian carcinoma by integrated bioinformatics analysis

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Published in 2021 at "Cancer Medicine"

DOI: 10.1002/cam4.3854

Abstract: To investigate the potential molecular mechanism of ovarian cancer (OC) evolution and immunological correlation using the integrated bioinformatics analysis. read more here.

Keywords: mir 378d; integrated bioinformatics; bioinformatics analysis; identification meg8 ... See more keywords
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Identification of aberrantly methylated differentially expressed genes in breast cancer by integrated bioinformatics analysis

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Published in 2019 at "Journal of Cellular Biochemistry"

DOI: 10.1002/jcb.28904

Abstract: Abnormal DNA methylation has been demonstrated to drive breast cancer tumorigenesis. Thus, this study aimed to explore differentially expressed biomarkers driven by aberrant methylation in breast cancer and explore potential pathological mechanisms using comprehensive bioinformatics… read more here.

Keywords: identification aberrantly; aberrantly methylated; breast cancer; bioinformatics analysis ... See more keywords

Integrative Bioinformatics Analysis and Experimental Study of NLRP12 Reveal Its Prognostic Value and Potential Functions in Ovarian Cancer

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Published in 2024 at "Molecular Carcinogenesis"

DOI: 10.1002/mc.23854

Abstract: NLRP12 plays a significant role in cellular functional behavior and immune homeostasis, influencing inflammation, tumorigenesis, and prognosis. This study aimed to explore its specific effects on the tumor microenvironment (TME) and its contribution to heterogeneity… read more here.

Keywords: cancer; bioinformatics analysis; analysis experimental; ovarian cancer ... See more keywords
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Bioinformatics Analysis of Functional Associations of PTMs.

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Published in 2017 at "Methods in molecular biology"

DOI: 10.1007/978-1-4939-6783-4_14

Abstract: Post-translational modifications (PTMs) are an important source of protein regulation; they fine-tune the function, localization, and interaction with other molecules of the majority of proteins and are partially responsible for their multifunctionality. Usually, proteins have… read more here.

Keywords: associations ptms; functional associations; bioinformatics analysis; analysis functional ... See more keywords

Identification of key genes in benign prostatic hyperplasia using bioinformatics analysis

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Published in 2021 at "World Journal of Urology"

DOI: 10.1007/s00345-021-03625-5

Abstract: This study aimed to identify differentially expressed genes (DEGs) and pathways in benign prostatic hyperplasia (BPH) by comprehensive bioinformatics analysis. Data of the gene expression microarray (GSE6099) were downloaded from GEO database. DEGs were obtained… read more here.

Keywords: degs; benign prostatic; analysis; bioinformatics analysis ... See more keywords

Identification of the entosis-related prognostic signature and tumour microenvironment in hepatocellular carcinoma on the basis of bioinformatics analysis and experimental validation

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Published in 2025 at "Clinical and Experimental Medicine"

DOI: 10.1007/s10238-025-01580-8

Abstract: Liver cancer ranks among the deadliest cancers worldwide. Entosis, a recently uncovered method of cell death, has not yet been fully explored for its relevance to HCC. A bioinformatics analysis was performed to determine the… read more here.

Keywords: entosis related; bioinformatics analysis; entosis; risk ... See more keywords

Identification of ITGA3 as an Oncogene in Human Tongue Cancer via Integrated Bioinformatics Analysis

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Published in 2018 at "Current Medical Science"

DOI: 10.1007/s11596-018-1935-9

Abstract: SummaryHuman tongue cancer (TC) is an aggressive malignancy with a very poor prognosis. There is an urgent need to elucidate the underlying molecular mechanisms involved in TC progression. mRNA expression profiles play a vital role… read more here.

Keywords: analysis; bioinformatics analysis; tongue cancer; cancer ... See more keywords

Bioinformatics analysis of recurrent deletion regions in neuroblastoma

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Published in 2022 at "Medical Oncology"

DOI: 10.1007/s12032-021-01639-y

Abstract: Neuroblastoma (NB) is the most common extra-cranial solid tumor in childhood. Very few genes in recurrent deletion regions have been identified as tumor suppressors for NB, and interactions among proteins encoded by genes in these… read more here.

Keywords: bioinformatics analysis; deletion regions; network; deletion ... See more keywords

Bioinformatics analysis of PAE family in Populus trichocarpa and responsiveness to carbon and nitrogen treatment

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Published in 2021 at "3 Biotech"

DOI: 10.1007/s13205-021-02918-1

Abstract: Plant Pectin acetylesterase (PAE) belongs to family CE13 of carbohydrate esterases in the CAZy database. The ability of PAE to regulate the degree of acetylation of pectin, an important polysaccharide in the cell wall, affects… read more here.

Keywords: nitrogen; populus; populus trichocarpa; family ... See more keywords
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Integrated Bioinformatics Analysis for the Screening of Associated Pathways and Therapeutic Drugs in Coronavirus Disease 2019

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Published in 2020 at "Archives of Medical Research"

DOI: 10.1016/j.arcmed.2020.11.009

Abstract: Background COVID-19 caused by a novel coronavirus, a severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), has recently broken out worldwide. Up to now, the development of vaccine is still in the stage of clinical… read more here.

Keywords: analysis; disease; coronavirus; bioinformatics analysis ... See more keywords