Screening and bioinformatics analysis of a ceRNA network based on the circular RNAs, miRNAs, and mRNAs in pan‐cancer
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Medicine"
DOI: 10.1002/cam4.3375
Abstract: The pan‐cancer analysis has recently brought us into a novel level of cancer research. Nowadays, the Circular RNAs (circRNAs) is becoming increasingly important in the occurrence and progression of tumors. Nevertheless, the specific expression patterns… read more here.
Keywords: pan cancer; circular rnas; bioinformatics analysis; screening bioinformatics ... See more keywords
Identification of MEG8/miR‐378d/SOBP axis as a novel regulatory network and associated with immune infiltrates in ovarian carcinoma by integrated bioinformatics analysis
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Medicine"
DOI: 10.1002/cam4.3854
Abstract: To investigate the potential molecular mechanism of ovarian cancer (OC) evolution and immunological correlation using the integrated bioinformatics analysis. read more here.
Keywords: mir 378d; integrated bioinformatics; bioinformatics analysis; identification meg8 ... See more keywords
Identification of aberrantly methylated differentially expressed genes in breast cancer by integrated bioinformatics analysis
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28904
Abstract: Abnormal DNA methylation has been demonstrated to drive breast cancer tumorigenesis. Thus, this study aimed to explore differentially expressed biomarkers driven by aberrant methylation in breast cancer and explore potential pathological mechanisms using comprehensive bioinformatics… read more here.
Keywords: identification aberrantly; aberrantly methylated; breast cancer; bioinformatics analysis ... See more keywords
Bioinformatics Analysis of Functional Associations of PTMs.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6783-4_14
Abstract: Post-translational modifications (PTMs) are an important source of protein regulation; they fine-tune the function, localization, and interaction with other molecules of the majority of proteins and are partially responsible for their multifunctionality. Usually, proteins have… read more here.
Keywords: associations ptms; functional associations; bioinformatics analysis; analysis functional ... See more keywords
Identification of key genes in benign prostatic hyperplasia using bioinformatics analysis
Sign Up to like & getrecommendations! Published in 2021 at "World Journal of Urology"
DOI: 10.1007/s00345-021-03625-5
Abstract: This study aimed to identify differentially expressed genes (DEGs) and pathways in benign prostatic hyperplasia (BPH) by comprehensive bioinformatics analysis. Data of the gene expression microarray (GSE6099) were downloaded from GEO database. DEGs were obtained… read more here.
Keywords: degs; benign prostatic; analysis; bioinformatics analysis ... See more keywords
Identification of ITGA3 as an Oncogene in Human Tongue Cancer via Integrated Bioinformatics Analysis
Sign Up to like & getrecommendations! Published in 2018 at "Current Medical Science"
DOI: 10.1007/s11596-018-1935-9
Abstract: SummaryHuman tongue cancer (TC) is an aggressive malignancy with a very poor prognosis. There is an urgent need to elucidate the underlying molecular mechanisms involved in TC progression. mRNA expression profiles play a vital role… read more here.
Keywords: analysis; bioinformatics analysis; tongue cancer; cancer ... See more keywords
Bioinformatics analysis of recurrent deletion regions in neuroblastoma
Sign Up to like & getrecommendations! Published in 2022 at "Medical Oncology"
DOI: 10.1007/s12032-021-01639-y
Abstract: Neuroblastoma (NB) is the most common extra-cranial solid tumor in childhood. Very few genes in recurrent deletion regions have been identified as tumor suppressors for NB, and interactions among proteins encoded by genes in these… read more here.
Keywords: bioinformatics analysis; deletion regions; network; deletion ... See more keywords
Bioinformatics analysis of PAE family in Populus trichocarpa and responsiveness to carbon and nitrogen treatment
Sign Up to like & getrecommendations! Published in 2021 at "3 Biotech"
DOI: 10.1007/s13205-021-02918-1
Abstract: Plant Pectin acetylesterase (PAE) belongs to family CE13 of carbohydrate esterases in the CAZy database. The ability of PAE to regulate the degree of acetylation of pectin, an important polysaccharide in the cell wall, affects… read more here.
Keywords: nitrogen; populus; populus trichocarpa; family ... See more keywords
Integrated Bioinformatics Analysis for the Screening of Associated Pathways and Therapeutic Drugs in Coronavirus Disease 2019
Sign Up to like & getrecommendations! Published in 2020 at "Archives of Medical Research"
DOI: 10.1016/j.arcmed.2020.11.009
Abstract: Background COVID-19 caused by a novel coronavirus, a severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), has recently broken out worldwide. Up to now, the development of vaccine is still in the stage of clinical… read more here.
Keywords: analysis; disease; coronavirus; bioinformatics analysis ... See more keywords
Bioinformatics analysis of non-synonymous variants in the KLF genes related to cardiac diseases.
Sign Up to like & getrecommendations! Published in 2018 at "Gene"
DOI: 10.1016/j.gene.2018.01.085
Abstract: Kruppel-like Factors (KLF) are responsible for regulating many genes involved in physiological and pathological processes. They are characterized by three conserved zinc-fingers in the DNA-binding domain, wherein mutations could affect the binding efficiency and transcription… read more here.
Keywords: related cardiac; cardiac diseases; bioinformatics analysis; synonymous variants ... See more keywords
Identification of Skt11-regulated genes in chondrocytes by integrated bioinformatics analysis.
Sign Up to like & getrecommendations! Published in 2018 at "Gene"
DOI: 10.1016/j.gene.2018.08.013
Abstract: SKT11, an important tumor suppressor, is a member of the serine/threonine kinase family and plays a crucial role in tumor invasion and metastasis by activated adenine monophosphate-activated protein kinase (AMPK) and AMPK-related kinase proteins. However,… read more here.
Keywords: analysis; regulated genes; bioinformatics analysis; skt11 ... See more keywords