Articles with "bioinformatics approach" as a keyword



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Identification and validation of a miRNA-based prognostic signature for cervical cancer through an integrated bioinformatics approach

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Published in 2020 at "Scientific Reports"

DOI: 10.1038/s41598-020-79337-4

Abstract: Cervical cancer is the fourth most common cancer in women worldwide. Increasing evidence has shown that miRNAs are related to the progression of cervical cancer. However, the mechanisms that affect the prognosis of cancer are… read more here.

Keywords: identification validation; bioinformatics approach; cervical cancer; integrated bioinformatics ... See more keywords
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Abstract LB173: A bioinformatics approach to determine the potential benefit of blocking both Galectin-1 and Galectin-3 in cancer

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Published in 2023 at "Cancer Research"

DOI: 10.1158/1538-7445.am2023-lb173

Abstract: Galectins are a family of Beta-galactoside-binding lectins that control numerous cellular processes in health and disease, including fibrosis, carcinogenesis and tumour immune evasion. Evidence is starting to emerge that blockade of more than one galectin… read more here.

Keywords: gal gal; bioinformatics approach; benefit; galectin ... See more keywords
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Bioinformatics approach to identify the influences of SARS-COV2 infections on atherosclerosis

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Published in 2022 at "Frontiers in Cardiovascular Medicine"

DOI: 10.3389/fcvm.2022.907665

Abstract: Coronavirus disease (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been a global pandemic since early 2020. Understanding the relationship between various systemic disease and COVID-19 through disease ontology (DO) analysis, an… read more here.

Keywords: approach identify; disease; bioinformatics approach; atherosclerosis ... See more keywords
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Functional Prediction and Assignment of Methanobrevibacter ruminantium M1 Operome Using a Combined Bioinformatics Approach

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Published in 2020 at "Frontiers in Genetics"

DOI: 10.3389/fgene.2020.593990

Abstract: Methanobrevibacter ruminantium M1 (MRU) is a rod-shaped rumen methanogen with the ability to use H2 and CO2, and formate as substrates for methane formation in the ruminants. Enteric methane emitted from this organism can also… read more here.

Keywords: bioinformatics approach; combined bioinformatics; physiology; using combined ... See more keywords
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An Integrated Proteomics and Bioinformatics Approach Reveals the Anti-inflammatory Mechanism of Carnosic Acid

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Published in 2018 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2018.00370

Abstract: Drastic macrophages activation triggered by exogenous infection or endogenous stresses is thought to be implicated in the pathogenesis of various inflammatory diseases. Carnosic acid (CA), a natural phenolic diterpene extracted from Salvia officinalis plant, has… read more here.

Keywords: anti inflammatory; mechanism; bioinformatics approach; proteomics bioinformatics ... See more keywords
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A Bioinformatics Approach to MicroRNA-Sequencing Analysis Based on Human Saliva Samples of Patients with Endometriosis

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms23148045

Abstract: Endometriosis, defined by the presence of endometrium-like tissue outside the uterus, affects 2–10% of the female population, i.e., around 190 million women, worldwide. The aim of the prospective ENDO-miRNA study was to develop a bioinformatics… read more here.

Keywords: endometriosis; sequencing analysis; saliva samples; bioinformatics approach ... See more keywords
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Bioinformatics approach reveals the key role of C-X-C motif chemokine receptor 2 in endometriosis development

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Published in 2018 at "Molecular Medicine Reports"

DOI: 10.3892/mmr.2018.9275

Abstract: Endometriosis is a common gynecological disease, affecting 6–10% of women of reproductive age. The precise mechanisms underlying the development of endometriosis remain unclear. In the present study, a bioinformatics approach was applied to systematically identify… read more here.

Keywords: endometriosis; bioinformatics approach; motif chemokine; gene ... See more keywords
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Identification of protein complexes associated with myocardial infarction using a bioinformatics approach

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Published in 2018 at "Molecular Medicine Reports"

DOI: 10.3892/mmr.2018.9414

Abstract: Myocardial infarction (MI) is a leading cause of mortality and disability worldwide. Determination of the molecular mechanisms underlying the disease is crucial for identifying possible therapeutic targets and designing effective treatments. On the basis that… read more here.

Keywords: protein; identification protein; myocardial infarction; bioinformatics approach ... See more keywords