Bioinformatics Approaches for Analyzing Multigene Families Encoding Immune Receptors.
Sign Up to like & getrecommendations! Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1944-5_11
Abstract: Genome sequences are quickly becoming available from a variety of organisms, providing researchers with an abundance of previously inaccessible information and an important source of insight into immune mechanisms. There are a variety of methods… read more here.
Keywords: immune receptors; genome sequences; approaches analyzing; bioinformatics approaches ... See more keywords
Bioinformatics Approaches to Predict Drug Responses from Genomic Sequencing.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7493-1_14
Abstract: Fulfilling the promises of precision medicine will depend on our ability to create patient-specific treatment regimens. Therefore, being able to translate genomic sequencing into predicting how a patient will respond to a given drug is… read more here.
Keywords: genomic sequencing; sequencing data; bioinformatics approaches; approaches predict ... See more keywords
p73-Governed miRNA Networks: Translating Bioinformatics Approaches to Therapeutic Solutions for Cancer Metastasis.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8982-9_2
Abstract: The transcription factor p73 synthesizes a large number of isoforms and presents high structural and functional homology with p53, a well-known tumor suppressor and a famous "Holy Grail" of anticancer targeting. p73 has attracted increasing… read more here.
Keywords: p73; transcription; governed mirna; bioinformatics approaches ... See more keywords
Leveraging big data bioinformatics approaches to extract knowledge from Staphylococcus aureus public omics data.
Sign Up to like & getrecommendations! Published in 2022 at "Critical reviews in microbiology"
DOI: 10.1080/1040841x.2022.2065905
Abstract: Staphylococcus aureus is a notorious pathogen posing challenges in the medical industry due to drug resistance and biofilm formation. The horizon of knowledge on S. aureus pathogenesis has expanded with the advancement of data-driven bioinformatics… read more here.
Keywords: bioinformatics approaches; staphylococcus aureus; leveraging big; omics data ... See more keywords
Bioinformatics Approaches Applied to the Discovery of Antifungal Peptides
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DOI: 10.3390/antibiotics12030566
Abstract: Antifungal peptides (AFPs) comprise a group of substances with a broad spectrum of activities and complex action mechanisms. They develop in nature via an evolutionary process resulting from the interactions between hosts and pathogens. The… read more here.
Keywords: bioinformatics approaches; approaches applied; antifungal peptides; discovery antifungal ... See more keywords
Integrated Genomic and Bioinformatics Approaches to Identify Molecular Links between Endocrine Disruptors and Adverse Outcomes
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Environmental Research and Public Health"
DOI: 10.3390/ijerph19010574
Abstract: Exposure to Endocrine Disrupting Chemicals (EDC) has been linked with several adverse outcomes. In this review, we examine EDCs that are pervasive in the environment and are of concern in the context of human, animal,… read more here.
Keywords: toxicology; bioinformatics approaches; genomic bioinformatics; adverse outcomes ... See more keywords
The First Snake Venom KTS/Disintegrins-Integrin Interactions Using Bioinformatics Approaches
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DOI: 10.3390/molecules28010325
Abstract: Snake venom contains a number of active molecules that have been shown to possess high anti-tumor activities; disintegrins are an excellent example among these. Their ability to interact and bind with integrins suggests that they… read more here.
Keywords: kts disintegrins; bioinformatics approaches; disintegrins integrin; kts ... See more keywords
Identification of Novel Genes in Osteoarthritic Fibroblast-Like Synoviocytes Using Next-Generation Sequencing and Bioinformatics Approaches
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Medical Sciences"
DOI: 10.7150/ijms.35611
Abstract: Synovitis in osteoarthritis (OA) the consequence of low grade inflammatory process caused by cartilage breakdown products that stimulated the production of pro-inflammatory mediators by fibroblast-like synoviocytes (FLS). FLS participate in joint homeostasis and low grade… read more here.
Keywords: fibroblast like; like synoviocytes; bioinformatics approaches; sequencing bioinformatics ... See more keywords