Complementary Genomic, Bioinformatics and Chemical Approaches Facilitate the Absolute Structure Assignment of Ionostatin, a Linear Polyketide from a Rare Marine-Derived Actinomycete.
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DOI: 10.1021/acschembio.0c00526
Abstract: A new linear type 1 polyketide, ionostatin (1) has been fully defined using a combined genomic and bioinformatics approach coupled with confirmatory chemical analyses. The 41 carbon-containing polyether is the product of the 101 kbp… read more here.
Keywords: polyketide; genomic bioinformatics; ionostatin; bioinformatics chemical ... See more keywords