Identification of post-translational modification-related biomarkers in ischemic stroke using bioinformatics and machine learning
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-22997-x
Abstract: Ischemic stroke (IS) remains a major clinical challenge due to the difficulty of early diagnosis and incomplete understanding of its pathological mechanisms. Post-translational modifications (PTMs) regulate key cellular processes in IS, but their roles as… read more here.
Keywords: ischemic stroke; bioinformatics machine; machine; machine learning ... See more keywords
Unveiling miRNA biomarkers for hypertrophic cardiomyopathy through integrated bioinformatics and machine learning analysis.
Sign Up to like & getrecommendations! Published in 2025 at "Acta cardiologica"
DOI: 10.1080/00015385.2025.2577015
Abstract: Abstract This study explores microRNAs (miRNAs) as biomarkers for hypertrophic cardiomyopathy (HCM), an inherited cardiac disease with clinical diversity and sudden death risk. Using bioinformatics and machine learning (ML), Gene Expression Omnibus (GEO) datasets were… read more here.
Keywords: analysis; bioinformatics machine; machine; machine learning ... See more keywords
Hispaglabridin B, a constituent of liquorice identified by a bioinformatics and machine learning approach, relieves proteinâenergy wasting by inhibiting forkhead box O1
Sign Up to like & getrecommendations! Published in 2019 at "British Journal of Pharmacology"
DOI: 10.1111/bph.14508
Abstract: Liquorice is the root of Glycyrrhiza glabra, which is a popular food in Europe and China that has previously shown benefits for skeletal fatigue and nutrient metabolism. However, the mechanism and active ingredients remain largely… read more here.
Keywords: identified bioinformatics; bioinformatics machine; hispaglabridin constituent; liquorice identified ... See more keywords
Employing a synergistic bioinformatics and machine learning framework to elucidate biomarkers associating asthma with pyrimidine metabolism genes
Sign Up to like & getrecommendations! Published in 2024 at "Respiratory Research"
DOI: 10.1186/s12931-024-02954-4
Abstract: Asthma, a prevalent chronic inflammatory disorder, is shaped by a multifaceted interplay between genetic susceptibilities and environmental exposures. Despite strides in deciphering its pathophysiological landscape, the intricate molecular underpinnings of asthma remain elusive. The focus… read more here.
Keywords: synergistic bioinformatics; pyrimidine metabolism; bioinformatics machine; metabolism ... See more keywords
Identification of core genes in intervertebral disc degeneration using bioinformatics and machine learning algorithms
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2024.1401957
Abstract: Background Intervertebral Disc Degeneration (IDD) is a major cause of lower back pain and a significant global health issue. However, the specific mechanisms of IDD remain unclear. This study aims to identify key genes and… read more here.
Keywords: disc degeneration; intervertebral disc; analysis; bioinformatics machine ... See more keywords
Special Issue on Bioinformatics and Machine Learning for Cancer Biology
Sign Up to like & getrecommendations! Published in 2022 at "Biology"
DOI: 10.3390/biology11030361
Abstract: Cancer is a leading cause of death worldwide, claiming millions of lives each year [...]. read more here.
Keywords: cancer; issue bioinformatics; bioinformatics machine; special issue ... See more keywords