Articles with "bioisosteric replacements" as a keyword



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Bioisosteric Replacements Extracted from High‐Quality Structures in the Protein Databank

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Published in 2018 at "ChemMedChem"

DOI: 10.1002/cmdc.201700679

Abstract: Bioisosterism is an important concept in the lead optimisation phase of drug discovery where the aim is to make modifications to parts of a molecule in order to improve some properties while maintaining others. We… read more here.

Keywords: extracted high; replacements extracted; bioisosteric replacements; high quality ... See more keywords