An improved biolistic delivery and analysis method for evaluation of DNA and CRISPR-Cas delivery efficacy in plant tissue
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-86549-9
Abstract: Biolistic delivery is widely used for genetic transformation but inconsistency between bombardment samples for transient gene expression analysis often hinders quantitative analyses. We developed a methodology to improve the consistency of biolistic delivery results by… read more here.
Keywords: dna; delivery; efficacy; biolistic delivery ... See more keywords
Carrier gas triggered controlled biolistic delivery of DNA and protein therapeutics from metal–organic frameworks
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Science"
DOI: 10.1039/d2sc04982a
Abstract: The efficacy and specificity of protein, DNA, and RNA-based drugs make them popular in the clinic; however, these drugs are often delivered via injection, requiring skilled medical personnel, and producing biohazardous waste. Here, we report… read more here.
Keywords: carrier gas; gas; dna; biolistic delivery ... See more keywords
Biolistic delivery of liposomes protected in metal-organic frameworks.
Sign Up to like & getrecommendations! Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2218247120
Abstract: Needle-and-syringe-based delivery has been the commercial standard for vaccine administration to date. With worsening medical personnel availability, increasing biohazard waste production, and the possibility of cross-contamination, we explore the possibility of biolistic delivery as an… read more here.
Keywords: based delivery; delivery; liposomes protected; protected metal ... See more keywords