NK cells are biologic and biochemical targets of 6-mercaptopurine in Crohn's disease patients.
Sign Up to like & getrecommendations! Published in 2017 at "Clinical immunology"
DOI: 10.1016/j.clim.2016.12.004
Abstract: NK cells, which contribute to immune defense against certain viral infections and neoplasia, are emerging as modifiers of chronic immunologic diseases including transplant rejection and autoimmune diseases. Immunobiology and genetic studies have implicated NK cells… read more here.
Keywords: biologic biochemical; cells biologic; targets mercaptopurine; disease ... See more keywords
Abstract B03: Biologic and biochemical interactions of NF1 GAP on KRAS G13x mutations
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Cancer Research"
DOI: 10.1158/1557-3125.ras18-b03
Abstract: KRAS mutations are common among 30% of cancers and promote tumor growth by constitutively activating the MAPK pathway independent of mitogenic stimuli. KRAS mutations at codons 12, 13, or 61 stabilize the KRAS-GTP complex by… read more here.
Keywords: gap; biologic biochemical; nf1 p120; kras g13d ... See more keywords