Antibiotic Use and the Persistence of Biologic Therapies in Patients With Psoriasis.
Sign Up to like & getrecommendations! Published in 2025 at "JAMA dermatology"
DOI: 10.1001/jamadermatol.2025.4427
Abstract: Importance The long-term effectiveness of biologic therapies in psoriasis may decline over time. Gut microbiota alterations induced by antibiotics have been proposed as a potential mechanism impairing biologic persistence. Objective To evaluate the association between… read more here.
Keywords: exposure; patients psoriasis; biologic therapies; therapies patients ... See more keywords
Deep molecular profiling of synovial biopsies in the STRAP trial identifies signatures predictive of treatment response to biologic therapies in rheumatoid arthritis
Sign Up to like & getrecommendations! Published in 2025 at "Nature Communications"
DOI: 10.1038/s41467-025-60987-9
Abstract: Approximately 40% of patients with rheumatoid arthritis do not respond to individual biologic therapies, while biomarkers predictive of treatment response are lacking. Here we analyse RNA-sequencing (RNA-Seq) of pre-treatment synovial tissue from the biopsy-based, precision-medicine… read more here.
Keywords: treatment; treatment response; response; biologic therapies ... See more keywords
Long-term effects of biologic therapies on peripheral blood eosinophils in patients with psoriasis: a 3-year single-center study
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Dermatological Treatment"
DOI: 10.1080/09546634.2019.1605139
Abstract: Abstract Background: Biologic therapies (BTs), etanercept, infliximab, adalimumab, and ustekinumab, are generally well-tolerated and safe agents in psoriasis management. Objectives: To determine the overall effect of BTs on peripheral blood eosinophil count (PBEc) and percentage… read more here.
Keywords: biologic therapies; patients psoriasis; peripheral blood; blood ... See more keywords
Emerging biologic therapies for hypercholesterolaemia
Sign Up to like & getrecommendations! Published in 2017 at "Expert Opinion on Biological Therapy"
DOI: 10.1080/14712598.2017.1341485
Abstract: ABSTRACT Introduction: LDL-cholesterol (LDL-C) is one of the most well-established risk factors for CV disease. Indeed, therapies that decrease LDL-C are proven to effectively reduce the risk of atherosclerotic CV disease. Monoclonal antibodies (mAbs) that… read more here.
Keywords: reduction; biologic therapies; risk; pcsk9 ... See more keywords
Immunogenicity of biologic therapies: causes and consequences
Sign Up to like & getrecommendations! Published in 2018 at "Expert Review of Clinical Immunology"
DOI: 10.1080/1744666x.2018.1468753
Abstract: ABSTRACT Introduction: Antibodies or fusion proteins termed biologics allow the targeted therapy of diseases. Many of these agents have proven superior efficacy and safety to conventional therapies, and subsequently revolutionized the management of numerous chronic… read more here.
Keywords: therapies causes; biologic therapies; immunogenicity biologic; immunogenicity ... See more keywords
Biologic Therapies in HIV/AIDS Patients with Inflammatory Diseases: A Systematic Review of the Literature.
Sign Up to like & getrecommendations! Published in 2023 at "AIDS patient care and STDs"
DOI: 10.1089/apc.2022.0197
Abstract: Biologic therapies have been increasingly developed and used for the treatment of severe inflammatory diseases. However, the safety and efficacy profile of biologic drugs in patients with HIV is not well established as this patient… read more here.
Keywords: safety; inflammatory diseases; systematic review; review literature ... See more keywords
Comparative Efficacy of Biologic Therapies for Inducing Response and Remission in Fistulizing Crohn's Disease: Systematic Review and Network Meta-Analysis of Randomized Controlled Trials.
Sign Up to like & getrecommendations! Published in 2022 at "Inflammatory bowel diseases"
DOI: 10.1093/ibd/izac103
Abstract: BACKGROUND The medical treatment of fistulizing Crohn's disease (CD) remains a challenge to clinicians. Over the last 20 years, biologic therapies have been the mainstay of medical treatment of fistulizing CD. The purpose of this… read more here.
Keywords: efficacy biologic; response remission; inducing response; remission ... See more keywords
Defining trajectories of response in patients with psoriasis treated with biologic therapies
Sign Up to like & getrecommendations! Published in 2021 at "British Journal of Dermatology"
DOI: 10.1111/bjd.20140
Abstract: The effectiveness and cost‐effectiveness of biologic therapies for psoriasis are significantly compromised by variable treatment responses. Thus, more precise management of psoriasis is needed. read more here.
Keywords: biologic therapies; patients psoriasis; response patients; psoriasis ... See more keywords
Combination of Antiplatelet Therapy in Psoriatic Diseases With Cardiovascular Comorbidities: A Thromboinflammatory Perspective in the Era of Biologic Therapies
Sign Up to like & getrecommendations! Published in 2025 at "Experimental Dermatology"
DOI: 10.1111/exd.70177
Abstract: Cardiovascular disease (CVD) remains the leading cause of death worldwide and represents the most significant comorbidity associated with psoriatic disease. Despite significant advancements in biologic therapies for psoriasis skin lesions, the lack of specific recommendations… read more here.
Keywords: therapy psoriatic; cardiovascular comorbidities; combination antiplatelet; biologic therapies ... See more keywords
Current use of biologic therapies for musculoskeletal disease: A survey of board‐certified equine specialists
Sign Up to like & getrecommendations! Published in 2022 at "Veterinary Surgery"
DOI: 10.1111/vsu.13805
Abstract: Abstract Objective To evaluate the use of mesenchymal stem cells (MSCs), autologous conditioned serum (ACS), platelet‐rich plasma (PRP), and autologous protein solution (APS) for the treatment of equine musculoskeletal disease by diplomates of the American… read more here.
Keywords: disease; prp; survey; musculoskeletal disease ... See more keywords
Knee Bursae: A Comprehensive Review of Clinical Evaluation, Imaging Differentiation, and the Expanding Role of Biologic Therapies.
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DOI: 10.1177/19476035251362434
Abstract: BackgroundKnee bursae are potential sources of anterior, medial, lateral, and posterior knee pain, yet many remain under-recognized in clinical practice. Emerging biological therapies offer promising, minimally invasive options for resistant bursitis, but high-level evidence is… read more here.
Keywords: review; knee bursae; role biologic; biologic therapies ... See more keywords