Can markers of biological age predict dependency in old age?
Sign Up to like & getrecommendations! Published in 2019 at "Biogerontology"
DOI: 10.1007/s10522-019-09795-5
Abstract: Recent research has shown that markers of biological age, such as leukocyte telomere length (LTL), epigenetic clocks and the frailty index (FI) are predictive of mortality and age-related diseases. However, whether these markers associate with… read more here.
Keywords: markers biological; age; old age; dependency ... See more keywords
The plasma metabolome as a predictor of biological aging in humans
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DOI: 10.1007/s11357-019-00123-w
Abstract: Chronological age is an important predictor of morbidity and mortality; however, it is unable to account for heterogeneity in the decline of physiological function and health with advancing age. Several attempts have been made to… read more here.
Keywords: plasma metabolome; age; metabolome predictor; biological age ... See more keywords
A toolkit for quantification of biological age from blood chemistry and organ function test data: BioAge.
Sign Up to like & getrecommendations! Published in 2021 at "GeroScience"
DOI: 10.1007/s11357-021-00480-5
Abstract: Methods to quantify biological aging are emerging as new measurement tools for epidemiology and population science and have been proposed as surrogate measures for healthy lifespan extension in geroscience clinical trials. Publicly available software packages… read more here.
Keywords: age; chemistry; bioage; blood chemistry ... See more keywords
The biological age linked to oxidative stress modifies breast cancer aggressiveness
Sign Up to like & getrecommendations! Published in 2018 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2018.03.012
Abstract: ABSTRACT The incidence of breast cancer increases with age until menopause, and breast cancer is more aggressive in younger women. The existence of epidemiological links between breast cancer and aging indicates that both processes share… read more here.
Keywords: breast cancer; mice; cancer; biological age ... See more keywords
Frailty Index as a clinical measure of biological age in psychiatry.
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DOI: 10.1016/j.jad.2020.03.015
Abstract: BACKGROUND Serious mental illnesses may be characterized by accelerated biological aging, and over the last years the research on the topic has been stimulated by studies exploring the molecular underpinnings of senescence. METHODS In the… read more here.
Keywords: age; biological age; measure biological; frailty index ... See more keywords
Multi-omics approaches to human biological age estimation
Sign Up to like & getrecommendations! Published in 2020 at "Mechanisms of Ageing and Development"
DOI: 10.1016/j.mad.2019.111192
Abstract: Multi-omics approach nowadays increasingly applied to molecular research in many fields of life sciences. Biogerontology is not an exception; multi-omics gives possibility to evaluate complex biomarkers (or panels) which consist of quantitative as well as… read more here.
Keywords: multi; multi omics; omics approaches; approaches human ... See more keywords
The Ground Zero of Organismal Life and Aging.
Sign Up to like & getrecommendations! Published in 2020 at "Trends in molecular medicine"
DOI: 10.1016/j.molmed.2020.08.012
Abstract: Cells may naturally proceed or be forced to transition to a state with a radically lower biological age, that is, be rejuvenated. Examples are the conversion of somatic cells to induced pluripotent stem cells and… read more here.
Keywords: organismal life; ground; ground zero; biological age ... See more keywords
A Cluster Randomized Controlled Trial on the Effects of Technology-aided Testing and Feedback on Physical Activity and Biological Age Among Employees in a Medium-sized Enterprise
Sign Up to like & getrecommendations! Published in 2017 at "Safety and Health at Work"
DOI: 10.1016/j.shaw.2017.03.003
Abstract: Background It has been suggested that engaging technology can empower individuals to be more proactive about their health and reduce their health risks. The aim of the present intervention was to study the effects of… read more here.
Keywords: age; biological age; physical activity; technology aided ... See more keywords
Pancreaticoduodenectomy in octogenarians: The importance of "biological age" on clinical outcomes.
Sign Up to like & getrecommendations! Published in 2021 at "Surgical oncology"
DOI: 10.1016/j.suronc.2021.101688
Abstract: INTRODUCTION With the prolongation of life expectancy, an increasing number of elderly patients are evaluated for pancreatic surgery. However, the influence of increasing age on outcomes after pancreaticoduodenectomy (PD) is still unclear, especially in octogenarians.… read more here.
Keywords: age; outcomes pancreaticoduodenectomy; octogenarians importance; pancreaticoduodenectomy octogenarians ... See more keywords
Chronological age or biological age: What drives the choice of adjuvant treatment in elderly breast cancer patients?
Sign Up to like & getrecommendations! Published in 2021 at "Translational Oncology"
DOI: 10.1016/j.tranon.2021.101300
Abstract: Highlights • The choice of adjuvant therapy in elderly patients should consider several factors.• There is a lack of universal and unique guidelines to define elderly patients.• Biological age is the result of genetics, lifestyle,… read more here.
Keywords: choice; age; chronological age; elderly patients ... See more keywords
Contribution of Biological Age–Predictive Biomarkers to Nutrition Research: A Systematic Review of the Current Evidence and Implications for Future Research and Clinical Practice
Sign Up to like & getrecommendations! Published in 2022 at "Advances in Nutrition"
DOI: 10.1093/advances/nmac060
Abstract: ABSTRACT The global population is living longer; however, not everyone ages at the same rate with regard to their physical and cognitive abilities and their vulnerability to certain diseases and death. This review aimed to… read more here.
Keywords: practice; research; review; future research ... See more keywords