Preparation and biological assessment of some aromatic hydrazones derived from hydrazides of phenolic acids and aromatic aldehydes
Sign Up to like & getrecommendations! Published in 2020 at "Heliyon"
DOI: 10.1016/j.heliyon.2020.e05019
Abstract: There has been substantial interest over the past many years in the design of novel chemical compounds containing the azomethine group (-NH-N=CH) and exhibiting various medicinal properties such as antibacterial, antiviral, antifungal, and anti-inflammatory activities.… read more here.
Keywords: hydrazones derived; aromatic hydrazones; assessment aromatic; aromatic aldehydes ... See more keywords
pH-responsive Chimeric Liposomes: From Nanotechnology to Biological Assessment.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2019.118849
Abstract: The utilization of liposomes in biomedical applications has greatly benefited the diagnosis and treatment of various diseases. These biomimetic nano-entities have been very useful in the clinical practice as drug delivery systems in their conventional… read more here.
Keywords: liposomes nanotechnology; nanotechnology biological; responsive chimeric; chimeric liposomes ... See more keywords
Lerisetron Analogues with Antimalarial Properties: Synthesis, Structure–Activity Relationship Studies, and Biological Assessment
Sign Up to like & getrecommendations! Published in 2020 at "ACS Omega"
DOI: 10.1021/acsomega.0c00327
Abstract: A phenotypic whole cell high-throughput screen against the asexual blood and liver stages of the malaria parasite identified a benzimidazole chemical series. Among the hits were the antiemetic benzimidazole drug Lerisetron 1 (IC50 NF54 =… read more here.
Keywords: lerisetron analogues; ic50 nf54; lerisetron; biological assessment ... See more keywords
Synthesis and biological assessment of novel cyanopyridine derivatives
Sign Up to like & getrecommendations! Published in 2019 at "Synthetic Communications"
DOI: 10.1080/00397911.2019.1616096
Abstract: Abstract New pyridine derivatives bearing p-dimethyl amino phenyl and p-bromophenyl moieties at position-4 and 6 have been prepared. The behavior of pyridone derivative 2 toward ethyl chloroacetate followed by hydrazine hydrate gave pyridinyl acetohydrazide derivative… read more here.
Keywords: novel cyanopyridine; assessment novel; synthesis biological; cyanopyridine derivatives ... See more keywords
Biological Assessment of Potential Exposure to Occupational Substances in Current Semiconductor Workers with at Least 5 Years of Employment
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Environmental Research and Public Health"
DOI: 10.3390/ijerph19148737
Abstract: Background: this study aimed to conduct a biological assessment of the potential exposure to carcinogenic substances in current semiconductor workers. Methods: A cross-sectional study was conducted on 306 semiconductor workers. The assessed biomarkers were as… read more here.
Keywords: assessment potential; acid; semiconductor workers; biological assessment ... See more keywords
Fabrication and Biological Assessment of Antidiabetic α-Mangostin Loaded Nanosponges: In Vitro, In Vivo, and In Silico Studies
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DOI: 10.3390/molecules26216633
Abstract: Type 2 diabetes mellitus has been a major health issue with increasing morbidity and mortality due to macrovascular and microvascular complications. The urgent need for improved methods to control hyperglycemic complications reiterates the development of… read more here.
Keywords: antidiabetic mangostin; loaded nanosponges; mangostin loaded; assessment antidiabetic ... See more keywords
Biological Assessment of the NO-Dependent Endothelial Function
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27227921
Abstract: Nitric oxide (NO) is implicated in numerous physiological processes, including vascular homeostasis. Reduced NO bioavailability is a hallmark of endothelial dysfunction, a prequel to many cardiovascular diseases. Biomarkers of an early NO-dependent endothelial dysfunction obtained… read more here.
Keywords: function; dependent endothelial; endothelial dysfunction; endothelial function ... See more keywords