Field-programmable biological circuits and configurable (bio)logic blocks for distributed biological computing
Sign Up to like & getrecommendations! Published in 2021 at "Computers in biology and medicine"
DOI: 10.1016/j.compbiomed.2020.104109
Abstract: Synthetic biology applications often require engineered computing structures, which can be programmed to process the information in a given way. However, programming of these structures usually requires significant amount of trial-and-error genetic engineering. This process… read more here.
Keywords: biological circuits; configurable bio; field; biology ... See more keywords
Implementing re-configurable biological computation with distributed multicellular consortia
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac1120
Abstract: Abstract The use of synthetic biological circuits to deal with numerous biological challenges has been proposed in several studies, but its implementation is still remote. A major problem encountered is the complexity of the cellular… read more here.
Keywords: computation; computation distributed; implementing configurable; biological circuits ... See more keywords
Designing Biological Circuits: Synthetic Biology Within the Operon Model and Beyond.
Sign Up to like & getrecommendations! Published in 2021 at "Annual review of biochemistry"
DOI: 10.1146/annurev-biochem-013118-111914
Abstract: In 1961, Jacob and Monod proposed the operon model of gene regulation. At the model's core was the modular assembly of regulators, operators, and structural genes. To illustrate the composability of these elements, Jacob and… read more here.
Keywords: biochemistry; operon model; biological circuits; synthetic biology ... See more keywords