Discordance between doctor and patient assessments and non-adherence to subcutaneous biological drugs
Sign Up to like & getrecommendations! Published in 2019 at "Rheumatology International"
DOI: 10.1007/s00296-019-04304-w
Abstract: To estimate the agreement level between patient and physician assessment of disease activity and to explore whether agreement is associated with adherence to subcutaneous (SC) biological drugs in rheumatoid arthritis (RA). Cross-sectional study of RA… read more here.
Keywords: agreement; adherence subcutaneous; subcutaneous biological; disease activity ... See more keywords
Building better biobetters: from fundamentals to industrial application.
Sign Up to like & getrecommendations! Published in 2021 at "Drug discovery today"
DOI: 10.1016/j.drudis.2021.08.009
Abstract: Biological drugs or biopharmaceuticals off patent open a large market for biosimilars and biobetters, follow-on biologics. Biobetters, in particular, are new drugs designed from existing ones with improved properties such as higher selectivity, stability, half-life… read more here.
Keywords: building better; industrial application; fundamentals industrial; biobetters fundamentals ... See more keywords
Polymeric nanomaterial strategies to encapsulate and deliver biological drugs: points to consider between methods.
Sign Up to like & getrecommendations! Published in 2023 at "Biomaterials science"
DOI: 10.1039/d2bm01594c
Abstract: Biological drugs (BDs) play an increasingly irreplaceable role in treating various diseases such as cancer, and cardiovascular and neurodegenerative diseases. The market share of BDs is increasingly promising. However, the effectiveness of BDs is currently… read more here.
Keywords: strategies encapsulate; deliver biological; polymeric nanomaterial; nanomaterial strategies ... See more keywords
Are biological drugs effective and safe in older severe asthmatics?
Sign Up to like & getrecommendations! Published in 2019 at "Expert Opinion on Drug Safety"
DOI: 10.1080/14740338.2019.1607838
Abstract: ABSTRACT Introduction: The treatment of asthma in older ages follows the recommendations of international guidelines for the management of asthma in younger ages, although older age has always represented an exclusion criterion for eligibility to… read more here.
Keywords: safety; effective safe; drugs effective; safe older ... See more keywords
Anaphylactic reactions to biological drugs.
Sign Up to like & getrecommendations! Published in 2020 at "Current Opinion in Allergy and Clinical Immunology"
DOI: 10.1097/aci.0000000000000666
Abstract: PURPOSE OF REVIEW This review summarizes the current knowledge of the pathogenic mechanisms of biologics-induced anaphylaxis, and the diagnostic and prophylactic strategies in the management of potentially reactive patients, to improve the safety profile of… read more here.
Keywords: biological drugs; anaphylactic reactions; immunology; antidrug antibodies ... See more keywords
Down syndrome and biological treatments in dermatology: Efficacy and safety in our real‐life experience and review of literature
Sign Up to like & getrecommendations! Published in 2023 at "Australasian Journal of Dermatology"
DOI: 10.1111/ajd.14006
Abstract: Down syndrome (DS) is the most common chromosomal disorder; several dermatological conditions are common in these patients; among them, psoriasis and atopic dermatitis can be frequently encountered. From 2017 to today, we retrospectively identified 4… read more here.
Keywords: syndrome biological; dermatology; efficacy; life ... See more keywords
Management of long‐term therapy with biological drugs in psoriatic patients with latent tuberculosis infection in real life setting
Sign Up to like & getrecommendations! Published in 2017 at "Dermatologic Therapy"
DOI: 10.1111/dth.12503
Abstract: Psoriatic patients with latent tuberculosis infection (LTBI) need a prophylaxis before starting a treatment with biological drugs. The aim of this study is to investigate the safety and efficacy of prophylaxis of LTBI in psoriatic… read more here.
Keywords: psoriatic patients; treatment; infection; tuberculosis ... See more keywords
Testing of Coding Algorithms for Inflammatory Bowel Disease Identification, as Indication for Use of Biological Drugs, Using a Claims Database from Southern Italy
Sign Up to like & getrecommendations! Published in 2023 at "Clinical Epidemiology"
DOI: 10.2147/clep.s383738
Abstract: Background Inflammatory bowel diseases (IBDs), Crohn’s disease (CD) and ulcerative colitis (UC), are chronic diseases that have been increasingly treated with biological drugs in recent years. Newly developed coding algorithms for IBD identification using claims… read more here.
Keywords: coding algorithms; biological drugs; exemption; use ... See more keywords
Anti-IL5 Therapies for Severe Eosinophilic Asthma: Literature Review and Practical Insights
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Asthma and Allergy"
DOI: 10.2147/jaa.s258594
Abstract: Abstract Severe refractory asthma (SRA) still has a high economic and social impact, including a reduction in quality of life (QoL), productivity, a greater risk of exacerbations and emergency department (ED) visits. Another major issue… read more here.
Keywords: eosinophilic asthma; biological drugs; review; therapies severe ... See more keywords
New Indications of Biological Drugs in Allergic and Immunological Disorders: Beyond Asthma, Urticaria, and Atopic Dermatitis
Sign Up to like & getrecommendations! Published in 2023 at "Biomedicines"
DOI: 10.3390/biomedicines11020236
Abstract: Asthma, chronic urticaria, and atopic dermatitis are some of the most numerous allergic diseases affecting children. Recent advances in the understanding of their specific intracellular molecular pathways have led to the approval of monoclonal antibodies… read more here.
Keywords: atopic dermatitis; new indications; biological drugs; urticaria atopic ... See more keywords
Quality of Life (QoL) in Patients with Chronic Inflammatory Bowel Diseases: How Much Better with Biological Drugs?
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Personalized Medicine"
DOI: 10.3390/jpm13060947
Abstract: Background: Inflammatory bowel diseases (IBDs), including ulcerative colitis (UC) and Crohn’s disease (CD), are chronic and disabling diseases that affect patient health-related quality of life (HRQoL). IBD patients are frequently exposed to high levels of… read more here.
Keywords: ibd patients; inflammatory bowel; life; biological drugs ... See more keywords