The clinical relative biological effectiveness and prostate‐specific antigen kinetics of carbon‐ion radiotherapy in low‐risk prostate cancer
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.5045
Abstract: To evaluate the clinical relative biological effectiveness (RBE) of carbon‐ion radiotherapy (C‐ion RT) for prostate cancer. read more here.
Keywords: biological effectiveness; prostate; clinical relative; relative biological ... See more keywords
A double-strand-break model for the relative biological effectiveness of electrons based on ionization clustering.
Sign Up to like & getrecommendations! Published in 2022 at "Medical physics"
DOI: 10.1002/mp.15796
Abstract: BACKGROUND The effectiveness of ionizing radiation regarding DNA damage induction depends on its spatial energy deposition pattern. For electrons an increased effectiveness is observed at low kinetic energies due to the enhanced density of energy… read more here.
Keywords: biological effectiveness; model; double strand; relative biological ... See more keywords
Effect of boron compounds on the biological effectiveness of proton therapy.
Sign Up to like & getrecommendations! Published in 2022 at "Medical physics"
DOI: 10.1002/mp.15824
Abstract: PURPOSE We assessed whether adding sodium borocaptate (BSH) or 4-borono-L-phenylalanine (BPA) to cells irradiated with proton beams influenced the biological effectiveness of those beams against prostate cancer cells to investigate if the alpha particles generated… read more here.
Keywords: du145 cells; biological effectiveness; effectiveness proton; h2ax 53bp1 ... See more keywords
Comparison of integrated biological effectiveness of eye plaques with 125I and 103Pd photon sources using equivalent uniform RBE-weighted dose.
Sign Up to like & getrecommendations! Published in 2025 at "Medical physics"
DOI: 10.1002/mp.70152
Abstract: The COMS (Collaborative Ocular Melanoma Study) eye plaques are based on the application of low‐energy photon sources such as iodine‐125 (125I) and palladium‐103 (103Pd). Compared to 125I, 103Pd is characterized by different radiobiological and physical… read more here.
Keywords: biological effectiveness; photon sources; eye plaques; 125i 103pd ... See more keywords
Impact of respiratory motion on variable relative biological effectiveness in 4D-dose distributions of proton therapy
Sign Up to like & getrecommendations! Published in 2017 at "Acta Oncologica"
DOI: 10.1080/0284186x.2017.1354131
Abstract: Abstract Background: Organ motion during radiation therapy with scanned protons leads to deviations between the planned and the delivered physical dose. Using a constant relative biological effectiveness (RBE) of 1.1 linearly maps these deviations into… read more here.
Keywords: motion; recalculation; rbe; variable rbe ... See more keywords
Implementation of a double scattering nozzle for Monte Carlo recalculation of proton plans with variable relative biological effectiveness.
Sign Up to like & getrecommendations! Published in 2020 at "Physics in medicine and biology"
DOI: 10.1088/1361-6560/abc12d
Abstract: IntroductionA constant relative biological effectiveness (RBE) of 1.1 is currently used in clinical proton therapy. However, the RBE varies with factors such as dose level, linear energy transfer (LET) and tissue type. Multiple RBE models… read more here.
Keywords: rbe; variable rbe; double scattering; proton ... See more keywords
The impact of TP53 status of tumor cells including the type and the concentration of administered 10B delivery agents on compound biological effectiveness in boron neutron capture therapy
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Radiation Research"
DOI: 10.1093/jrr/rrad001
Abstract: Abstract Human head and neck squamous cell carcinoma cells transfected with mutant TP53 (SAS/mp53) or neo vector (SAS/neo) were inoculated subcutaneously into left hind legs of nude mice. After the subcutaneous administration of a 10B-carrier,… read more here.
Keywords: biological effectiveness; tumor; tumor cells; tp53 ... See more keywords
Incorporating boron distribution variations in microdosimetric kinetic model-based relative biological effectiveness calculations for boron neutron capture therapy.
Sign Up to like & getrecommendations! Published in 2024 at "Radiation protection dosimetry"
DOI: 10.1093/rpd/ncae158
Abstract: This study introduces the MKM_B model, an approach derived from the MKM model, designed to evaluate the biological effectiveness of Boron Neutron Capture Therapy (BNCT) in the face of challenges from varying microscopic boron distributions.… read more here.
Keywords: biological effectiveness; boron; cbe; model ... See more keywords
Biological effectiveness and relative biological effectiveness of ion beams for in‐vitro cell irradiation
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DOI: 10.1111/cas.15446
Abstract: Biological effectiveness and relative biological effectiveness are critical for proton and ion beam radiotherapy. However, the relationship between the two quantities and physical character of ion beams is not well established. By analyzing 1188 sets… read more here.
Keywords: biological effectiveness; ion beam; relative biological; ion beams ... See more keywords
Abstract 1335: Comparison of X-ray and gamma-ray irradiators for in vitro and in vivo biological effectiveness
Sign Up to like & getrecommendations! Published in 2025 at "Cancer Research"
DOI: 10.1158/1538-7445.am2025-1335
Abstract: The Cesium Irradiator Replacement Program (CIRP) was established in 2014 to replace radioisotope-based irradiators with non-radioactive alternatives, such as X-rays. As most dosimetry is based on 137Cs irradiators, transitioning to X-ray systems has presented challenges… read more here.
Keywords: biological effectiveness; ray irradiators; radiation; vitro vivo ... See more keywords
Dose-Dependent Transmissibility of Chromosome Aberrations in Human Lymphocytes at First Mitosis. II. Biological Effectiveness of Heavy Charged Particles Versus Gamma Rays
Sign Up to like & getrecommendations! Published in 2023 at "Radiation Research"
DOI: 10.1667/rade-22-00141.1
Abstract: Chromosome aberrations (CAs) are large scale structural rearrangements to the genome that have been used as a proxy endpoint of mutagenic and carcinogenic potential. And yet, many types of CAs are incapable of causing either… read more here.
Keywords: chromosome aberrations; biological effectiveness; gamma; human lymphocytes ... See more keywords