The de Rham-Hodge Analysis and Modeling of Biomolecules.
Sign Up to like & getrecommendations! Published in 2020 at "Bulletin of mathematical biology"
DOI: 10.1007/s11538-020-00783-2
Abstract: Biological macromolecules have intricate structures that underpin their biological functions. Understanding their structure-function relationships remains a challenge due to their structural complexity and functional variability. Although de Rham-Hodge theory, a landmark of twentieth-century mathematics, has… read more here.
Keywords: rham hodge; analysis; mathematics; biological macromolecules ... See more keywords
Damages to biological macromolecules in gonadal subcellular fractions of scallop Chlamys farreri following benzo[a]pyrene exposure: Contribution to inhibiting gonadal development and reducing fertility.
Sign Up to like & getrecommendations! Published in 2021 at "Environmental pollution"
DOI: 10.1016/j.envpol.2021.117084
Abstract: Benzo[a]pyrene (B[a]P), a representative polycyclic aromatic hydrocarbon (PAH) compound in marine ecosystem, has great potential for chronic toxicity to marine animals. It is becoming increasingly apparent that reproductive system is the major target of B[a]P,… read more here.
Keywords: biological macromolecules; gonadal subcellular; gonadal development; subcellular fractions ... See more keywords
Effects of flavonoids incorporated biological macromolecules based scaffolds in bone tissue engineering.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2017.09.014
Abstract: Skeletal tissue damage caused by trauma, injury, or disease can often result in considerable morbidity and the need for new, more reliable strategies for skeletal regeneration. So, to address the unmet need for bone augmentation,… read more here.
Keywords: biological macromolecules; bone tissue; tissue engineering; tissue ... See more keywords
Biological macromolecules based targeted nanodrug delivery systems for the treatment of intracellular infections.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2018.01.030
Abstract: Intracellular infections are tricky to treat, the reason being the poor penetration of antibiotics/antimycotics into the microbial niche (host cell). Macrophages are primary targets of facultative and obligate intracellular bacteria/fungi to be abused as host… read more here.
Keywords: intracellular infections; macromolecules based; biological macromolecules; targeted nanodrug ... See more keywords
Distribution of tightly and loosely bound water in biological macromolecules and age-related diseases.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2018.06.187
Abstract: This mini-review article is focused on publications devoted to the changes in water binding energy and content of bound water in biological tissues during aging processes, when bound water lost from the hydration layer becomes… read more here.
Keywords: water biological; biological macromolecules; water; age ... See more keywords
Paramagnetic Chemical Probes for Studying Biological Macromolecules.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical reviews"
DOI: 10.1021/acs.chemrev.1c00708
Abstract: Paramagnetic chemical probes have been used in electron paramagnetic resonance (EPR) and nuclear magnetic resonance (NMR) spectroscopy for more than four decades. Recent years witnessed a great increase in the variety of probes for the… read more here.
Keywords: probes studying; spectroscopy; paramagnetic chemical; biological macromolecules ... See more keywords
Impact of Increased Sonication-Induced Dispersion of Sepiolite on Its Interaction with Biological Macromolecules and Toxicity/Proliferation in Human Cells
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c06391
Abstract: Sepiolite is a natural clay silicate that is widely used, including biomedical applications; notably sepiolite shows promising features for the transfer of biological macromolecules into mammalian cells. However, before its use, such an approach should… read more here.
Keywords: sonication; biological macromolecules; toxicity; dispersion sepiolite ... See more keywords
Phosphorylation and sulfation share a common biosynthetic pathway, but extend biochemical and evolutionary diversity of biological macromolecules in distinct ways
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the Royal Society Interface"
DOI: 10.1098/rsif.2022.0391
Abstract: Phosphate and sulfate groups are integral to energy metabolism and introduce negative charges into biological macromolecules. One purpose of such modifications is to elicit precise binding/activation of protein partners. The physico-chemical properties of the two… read more here.
Keywords: sulfation share; phosphorylation sulfation; share common; phosphorylation ... See more keywords
X-ray radiation damage to biological macromolecules: further insights.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of synchrotron radiation"
DOI: 10.1107/s160057751602018x
Abstract: Despite significant progress made over more than 15 years of research, structural biologists are still grappling with the issue of radiation damage suffered by macromolecular crystals which is induced by the resultant radiation chemistry occurring… read more here.
Keywords: biological macromolecules; radiation damage; radiation; damage ... See more keywords
Approximating deformation fields for the analysis of continuous heterogeneity of biological macromolecules by 3D Zernike polynomials
Sign Up to like & getrecommendations! Published in 2021 at "IUCrJ"
DOI: 10.1107/s2052252521008903
Abstract: A new tool based on 3D Zernike polynomials is presented that allows the study of the continuous heterogeneity of biological macromolecules, revealing the structural relationships present among different states by the approximation of deformation fields. read more here.
Keywords: biological macromolecules; deformation fields; continuous heterogeneity; zernike polynomials ... See more keywords
Electrostatics in Computational Biophysics and Its Implications for Disease Effects
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms231810347
Abstract: This review outlines the role of electrostatics in computational molecular biophysics and its implication in altering wild-type characteristics of biological macromolecules, and thus the contribution of electrostatics to disease mechanisms. The work is not intended… read more here.
Keywords: biophysics; range; electrostatics computational; electrostatics ... See more keywords