Targetable Biological Mechanisms Implicated in Emergent Psychiatric Conditions Associated With SARS-CoV-2 Infection.
Sign Up to like & getrecommendations! Published in 2020 at "JAMA psychiatry"
DOI: 10.1001/jamapsychiatry.2020.2795
Abstract: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in 2019 and then rapidly led to a pandemic with widespread cases of SARS and excess mortality. In response, mitigation efforts (including social distancing, quarantining, and closing… read more here.
Keywords: infection; coronavirus; biological mechanisms; psychiatric conditions ... See more keywords
Turtles all the way down: do biological mechanisms for epidemiological observations always matter?
Sign Up to like & getrecommendations! Published in 2021 at "European Journal of Epidemiology"
DOI: 10.1007/s10654-021-00807-8
Abstract: Biological mechanisms are ubiquitous in reports of epidemiological research. Many researchers extensively elaborate on a biological potential mechanism underlying their findings under the assumption that the presence of one is somehow related to the quality… read more here.
Keywords: epidemiological observations; way biological; mechanisms epidemiological; biological mechanisms ... See more keywords
Electric field‐responsive nanoparticles and electric fields: physical, chemical, biological mechanisms and therapeutic prospects
Sign Up to like & getrecommendations! Published in 2019 at "Advanced Drug Delivery Reviews"
DOI: 10.1016/j.addr.2018.10.017
Abstract: &NA; Electric fields are among physical stimuli that have revolutionized therapy. Occurring endogenously or exogenously, the electric field can be used as a trigger for controlled drug release from electroresponsive drug delivery systems, can stimulate… read more here.
Keywords: electric fields; physical chemical; field; biological mechanisms ... See more keywords
The clinical impact and biological mechanisms of skeletal muscle aging.
Sign Up to like & getrecommendations! Published in 2019 at "Bone"
DOI: 10.1016/j.bone.2019.05.021
Abstract: Skeletal muscle is a highly plastic tissue that remarkably adapts to diverse stimuli including exercise, injury, disuse, and, as discussed here, aging. Humans achieve peak skeletal muscle mass and strength in mid-life and then experience… read more here.
Keywords: skeletal muscle; muscle; clinical impact; biological mechanisms ... See more keywords
Design of a randomized controlled trial examining the efficacy and biological mechanisms of web-prolonged exposure and present-centered therapy for PTSD among active-duty military personnel and veterans.
Sign Up to like & getrecommendations! Published in 2018 at "Contemporary clinical trials"
DOI: 10.1016/j.cct.2017.11.008
Abstract: Improved accessibility of effective and efficient evidence-based treatments (EBTs) for military personnel suffering with posttraumatic stress disorder (PTSD) is an urgent need to meet the growing demand for timely care. In addition, a better understanding… read more here.
Keywords: web based; military personnel; efficacy; based treatment ... See more keywords
An update to the advances in understanding distraction histogenesis: From biological mechanisms to novel clinical applications
Sign Up to like & getrecommendations! Published in 2020 at "Journal of orthopaedic translation"
DOI: 10.1016/j.jot.2020.09.003
Abstract: Abstract Purpose of review Over the past 3 decades, Ilizarov technique namely distraction histogenesis (DH) technique has been widely accepted and applied in orthopaedics and traumatology with outstanding clinical outcomes and emerging novel applications. This… read more here.
Keywords: technique; distraction histogenesis; bone; clinical applications ... See more keywords
Probing Biological Mechanisms with Chemical Tools.
Sign Up to like & getrecommendations! Published in 2020 at "Pharmacological research"
DOI: 10.1016/j.phrs.2020.104656
Abstract: Traditionally small molecules have mainly been used to inhibit biochemical activities of proteins, however such compounds can also be used to change the conformational energy landscape of proteins. Tool compounds that allosterically modulate protein conformations… read more here.
Keywords: chemical tools; probing biological; biological mechanisms; mechanisms chemical ... See more keywords
Biological mechanisms of non‐linear dose‐response for respirable mineral fibers
Sign Up to like & getrecommendations! Published in 2018 at "Toxicology and Applied Pharmacology"
DOI: 10.1016/j.taap.2018.06.016
Abstract: ABSTRACT Sufficiently high and prolonged inhalation exposures to some respirable elongated mineral particles (REMPs), notably including amphibole asbestos fibers, can increase risk of inflammation‐mediated diseases including malignant mesothelioma, pleural diseases, fibrosis, and lung cancer. Chronic… read more here.
Keywords: dose response; response; non linear; biological mechanisms ... See more keywords
Genetic analysis of probable sleep bruxism and its associations with clinical and behavioral traits.
Sign Up to like & getrecommendations! Published in 2023 at "Sleep"
DOI: 10.1093/sleep/zsad107
Abstract: STUDY OBJECTIVES Sleep bruxism (SB) can cause damage on teeth, headache and severe pain affecting both sleep and daily functioning. Yet despite the growing interest into bruxism, the underlying clinically relevant biological mechanisms remain unresolved.… read more here.
Keywords: analysis probable; sleep bruxism; bruxism; analysis ... See more keywords
Aspirin and cancer: biological mechanisms and clinical outcomes
Sign Up to like & getrecommendations! Published in 2022 at "Open Biology"
DOI: 10.1098/rsob.220124
Abstract: Evidence on aspirin and cancer comes from two main sources: (1) the effect of aspirin upon biological mechanisms in cancer, and (2) clinical studies of patients with cancer, some of whom take aspirin. A series… read more here.
Keywords: aspirin cancer; evidence; biological mechanisms; aspirin upon ... See more keywords
Gene Differential Expression and Interaction Networks Illustrate the Biomarkers and Molecular Biological Mechanisms of Unsaponifiable Matter in Kanglaite Injection for Pancreatic Ductal Adenocarcinoma
Sign Up to like & getrecommendations! Published in 2022 at "BioMed Research International"
DOI: 10.1155/2022/6229462
Abstract: Background Kanglaite injection (KLTi) has shown good clinical efficacy in the treatment of pancreatic ductal adenocarcinoma (PDAC). While previous studies have demonstrated the antitumor effects of the oil compounds in KLTi, it is unclear whether… read more here.
Keywords: molecular biological; ductal adenocarcinoma; biological mechanisms; pancreatic ductal ... See more keywords