Biological models in multiple sclerosis
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.24528
Abstract: Considering the etiology of multiple sclerosis (MS) is still unknown, experimental models resembling specific aspects of this immune‐mediated demyelinating human disease have been developed to increase the understanding of processes related to pathogenesis, disease evolution,… read more here.
Keywords: biological models; disease; multiple sclerosis; disease animal ... See more keywords
Cell Lines as Biological Models: Practical Steps for More Reliable Research.
Sign Up to like & getrecommendations! Published in 2019 at "Chemical research in toxicology"
DOI: 10.1021/acs.chemrestox.9b00215
Abstract: Research in toxicology relies on in vitro models such as cell lines. These living models are prone to change and may be described in publications with insufficient information or quality control testing. This article sets… read more here.
Keywords: research; biological models; cell lines; lines biological ... See more keywords
PyDREAM: high-dimensional parameter inference for biological models in python
Sign Up to like & getrecommendations! Published in 2018 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btx626
Abstract: Abstract Summary Biological models contain many parameters whose values are difficult to measure directly via experimentation and therefore require calibration against experimental data. Markov chain Monte Carlo (MCMC) methods are suitable to estimate multivariate posterior… read more here.
Keywords: high dimensional; parameter inference; biological models; pydream ... See more keywords
Genetic Alterations Featuring Biological Models to Tailor Clinical Management of Pancreatic Cancer Patients
Sign Up to like & getrecommendations! Published in 2020 at "Cancers"
DOI: 10.3390/cancers12051233
Abstract: Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer-related death worldwide. This high mortality rate is due to the disease’s lack of symptoms, resulting in a late diagnosis. Biomarkers and treatment options for… read more here.
Keywords: biological models; alterations featuring; featuring biological; pancreatic cancer ... See more keywords
Comparison of the Toxicity of Pristine Graphene and Graphene Oxide, Using Four Biological Models
Sign Up to like & getrecommendations! Published in 2021 at "Materials"
DOI: 10.3390/ma14154250
Abstract: There are numerous applications of graphene in biomedicine and they can be classified into several main areas: delivery systems, sensors, tissue engineering and biological agents. The growing biomedical field of applications of graphene and its… read more here.
Keywords: biological models; using four; graphene; toxicity pristine ... See more keywords
Biological Models of the Lower Human Airways—Challenges and Special Requirements of Human 3D Barrier Models for Biomedical Research
Sign Up to like & getrecommendations! Published in 2021 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics13122115
Abstract: In our review, we want to summarize the current status of the development of airway models and their application in biomedical research. We start with the very well characterized models composed of cell lines and… read more here.
Keywords: biological models; barrier; biomedical research; models lower ... See more keywords
Straight roads into nowhere – obvious and not-so-obvious biological models for ferrophobic surfaces
Sign Up to like & getrecommendations! Published in 2022 at "Beilstein Journal of Nanotechnology"
DOI: 10.3762/bjnano.13.111
Abstract: There are currently efforts to improve strategies for biomimetic approaches, to identify pitfalls and to provide recommendations for a successful biomimetic work flow. In this contribution, a case study of a concrete biomimetic project is… read more here.
Keywords: nowhere obvious; biological models; straight roads; surface ... See more keywords