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Published in 2019 at "Nature physics"
DOI: 10.1038/s41567-019-0598-1
Abstract: The circadian clock and the cell cycle are two biological oscillatory processes that coexist within individual cells. These two oscillators were found to interact, which can lead to their synchronization. Here, we develop a method…
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Keywords:
dimensional dynamics;
coupled biological;
biological oscillators;
dynamics two ... See more keywords
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Published in 2021 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btab623
Abstract: MOTIVATION Fundamental to biological study is identifying regulatory interactions. The recent surge in time-series data collection in biology provides a unique opportunity to infer regulations computationally. However, when components oscillate, model-free inference methods, while easily…
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Keywords:
time series;
causality biological;
model;
causality ... See more keywords
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Published in 2019 at "BMC Bioinformatics"
DOI: 10.1186/s12859-019-2630-y
Abstract: BackgroundDynamic modelling is a core element in the systems biology approach to understanding complex biosystems. Here, we consider the problem of parameter estimation in models of biological oscillators described by deterministic nonlinear differential equations. These…
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Keywords:
estimation;
estimation models;
models biological;
parameter estimation ... See more keywords